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    Eukaryotic translation initiation factor eIF2A family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 843652, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Eukaryotic translation initiation factor eIF2A family protein
    Primary source
    TAIR:AT1G73180
    Locus tag
    AT1G73180
    See related
    Araport:AT1G73180
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T18K17.15; T18K17_15
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (27517891..27521710)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene bonsai Neighboring gene Aquaporin-like superfamily protein Neighboring gene testis-expressed sequence 2-like protein (DUF2404) Neighboring gene hypothetical protein (DUF789)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
    2. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    3. MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Popescu SC, et al. Genes Dev, 2009 Jan 1. PMID 19095804, Free PMC Article
    4. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001124120.2
    NM_105977.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Eukaryotic translation initiation factor eIF2A family protein
    NP_001117592.1
    • Eukaryotic translation initiation factor eIF2A family protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), Eukaryotic translation initiation factor 2A, central region (InterPro:IPR013979), Translation initiation factor eIF-2A (InterPro:IPR011387), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943); BEST Arabidopsis thaliana protein match is: translation initiation factor 3B1 (TAIR:AT5G27640.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_565058.1
    • Eukaryotic translation initiation factor eIF2A family protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), Eukaryotic translation initiation factor 2A, central region (InterPro:IPR013979), Translation initiation factor eIF-2A (InterPro:IPR011387), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943); BEST Arabidopsis thaliana protein match is: translation initiation factor 3B1 (TAIR:AT5G27640.1); Has 898 Blast hits to 895 proteins in 262 species: Archae - 0; Bacteria - 8; Metazoa - 280; Fungi - 316; Plants - 125; Viruses - 0; Other Eukaryotes - 169 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      27517891..27521710
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105977.4 → NP_565058.1  Eukaryotic translation initiation factor eIF2A family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565058.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ETN5, Q8LG73, Q9CAT3
      Conserved Domains (3) summary
      COG5354
      Location:19 → 486
      COG5354; Uncharacterized protein, contains Trp-Asp (WD) repeat [General function prediction only]
      sd00039
      Location:280 → 312
      7WD40; WD40 repeat [structural motif]
      pfam08662
      Location:214 → 407
      eIF2A; Eukaryotic translation initiation factor eIF2A

    2. NM_001124120.2 → NP_001117592.1  Eukaryotic translation initiation factor eIF2A family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117592.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W866, B3H5L3
      Conserved Domains (4) summary
      COG2319
      Location:19 → 255
      WD40; WD40 repeat [General function prediction only]
      pfam08662
      Location:214 → 407
      eIF2A; Eukaryotic translation initiation factor eIF2A
      sd00039
      Location:280 → 312
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:272 → 390
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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