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    sequence-specific DNA binding transcription factor [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820165, updated on 18-Sep-2024

    Summary

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    Official Full Name
    sequence-specific DNA binding transcription factor
    Primary source
    TAIR:AT3G10040
    Locus tag
    AT3G10040
    See related
    Araport:AT3G10040
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    HRA1; HYPOXIA RESPONSE ATTENUATOR1
    Summary
    Encodes HRA1 (HYPOXIA RESPONSE ATTENUATOR1), a low oxygen-inducible transcription factor.
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (3096345..3098417, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene aspartate/glutamate/uridylate kinase family protein Neighboring gene tRNA-Arg Neighboring gene L-O-methylthreonine resistant 1 Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene TBP-associated factor 12

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A trihelix DNA binding protein counterbalances hypoxia-responsive transcriptional activation in Arabidopsis. Giuntoli B, et al. PLoS Biol, 2014 Sep. PMID 25226037, Free PMC Article
    2. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
    3. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Smit ME, et al. Plant Cell, 2020 Feb. PMID 31806676, Free PMC Article
    4. Transcriptional regulation of nitrogen-associated metabolism and growth. Gaudinier A, et al. Nature, 2018 Nov. PMID 30356219
    5. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111839.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
    acts_upstream_of_or_within negative regulation of gene expression IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of cellular response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    sequence-specific DNA binding transcription factor
    NP_187615.2
    • sequence-specific DNA binding transcription factors; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G76870.1); Has 3136 Blast hits to 1955 proteins in 249 species: Archae - 4; Bacteria - 147; Metazoa - 846; Fungi - 267; Plants - 330; Viruses - 57; Other Eukaryotes - 1485 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3096345..3098417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111839.3 → NP_187615.2  sequence-specific DNA binding transcription factor [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187615.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VCJ8, A0A384KQJ0, Q8RWY5, Q9SR69
      Conserved Domains (1) summary
      pfam13837
      Location:103 → 195
      Myb_DNA-bind_4; Myb/SANT-like DNA-binding domain
    Nucleotide Protein
    Heading Accession and Version

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