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    AOP1 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828100, updated on 18-Sep-2024

    Summary

    Official Symbol
    AOP1
    Official Full Name
    2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein
    Primary source
    TAIR:AT4G03070
    Locus tag
    AT4G03070
    See related
    Araport:AT4G03070
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AOP; AOP1.1; T4I9.5; T4I9_5
    Summary
    Encodes a possible 2-oxoglutarate-dependent dioxygenase that is involved in glucosinolate biosynthesis. The gene is expressed in all ecotypes examined but the enzymatic activity has not been determined experimentally. In Col, there is one copy of this gene (aka AOP1.1) but Ler contains two copies, AOP1.1 and a tightly linked AOP1.2.
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    Genomic context

    See AOP1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (1358267..1359698)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene BRI1 suppressor 1 (BSU1)-like 1 Neighboring gene sequence-specific DNA binding transcription factor ATNDX

    General gene information

    NM_116541.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 2-oxoglutarate-dependent dioxygenase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within glucosinolate biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein
    NP_192216.1
    • AOP1; FUNCTIONS IN: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; INVOLVED IN: glucosinolate biosynthetic process; LOCATED IN: membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein (TAIR:AT1G52820.1); Has 7341 Blast hits to 7267 proteins in 919 species: Archae - 0; Bacteria - 920; Metazoa - 64; Fungi - 670; Plants - 4573; Viruses - 0; Other Eukaryotes - 1114 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1358267..1359698
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116541.4NP_192216.1  2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192216.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZTA3
      UniProtKB/TrEMBL
      A0A654FLF2, Q944Z4
      Conserved Domains (3) summary
      PLN02365
      Location:14300
      PLN02365; 2-oxoglutarate-dependent dioxygenase
      pfam03171
      Location:187271
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
      pfam14226
      Location:1490
      DIOX_N; non-haem dioxygenase in morphine synthesis N-terminal