CIB22 LYR family of Fe/S cluster biogenesis protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: CIB22
Official Full Name: LYR family of Fe/S cluster biogenesis protein
Primary source: TAIR:AT4G34700
Locus tag: AT4G34700
See related: Araport:AT4G34700
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtCIB22; B22 subunit of eukaryotic mitochondrial Complex I; T4L20.280; T4L20_280
Summary: Encodes the B22 subunit of eukaryotic mitochondrial Complex I. Mutation in the gene display pleiotropic phenotypes including shorter roots, smaller plants and delayed flowering.
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Genomic context

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See CIB22 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 6

Sequence:: Chromosome: 4; NC_003075.7 (16556738..16559034)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data demonstrate that AtCIB22 (At4g34700) is essential for plant development and mitochondrial electron transport chains in Arabidopsis.
Title: A nuclear-encoded mitochondrial gene AtCIB22 is essential for plant development in Arabidopsis.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_119636.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial electron transport, NADH to ubiquinone	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within photorespiration	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrial membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in plant-type vacuole	HDA more info	PubMed
located_in plasma membrane	HDA more info	PubMed
part_of respiratory chain complex I	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: LYR family of Fe/S cluster biogenesis protein

NP_567970.1

LYR family of Fe/S cluster biogenesis protein; FUNCTIONS IN: catalytic activity; INVOLVED IN: photorespiration; LOCATED IN: mitochondrial membrane, plasma membrane, respiratory chain complex I; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

16556738..16559034

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_119636.4 → NP_567970.1 LYR family of Fe/S cluster biogenesis protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_567970.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O65692, Q56Z32, Q8LDS9, Q945M1

UniProtKB/TrEMBL

A0A654FVK2, A0A7G2F4T0

Conserved Domains (1) summary

cd20263
Location:16 → 92

Complex1_LYR_NDUFB9_LYRM3; LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) and similar proteins