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    ABCA8 ABC2 homolog 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823933, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ABCA8
    Official Full Name
    ABC2 homolog 7
    Primary source
    TAIR:AT3G47790
    Locus tag
    AT3G47790
    See related
    Araport:AT3G47790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABC2 homolog 7; ATATH7; ATH7; ATP-binding cassette A8
    Summary
    member of ATH subfamily
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    Genomic context

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    See ABCA8 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    17
    Sequence:
    Chromosome: 3; NC_003074.8 (17629530..17633942)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ABC2 homolog 5 Neighboring gene ABC2 homolog 6 Neighboring gene Galactose mutarotase-like superfamily protein Neighboring gene ncRNA Neighboring gene Calcineurin-like metallo-phosphoesterase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis thaliana ABC protein superfamily, a complete inventory. Sánchez-Fernández R, et al. J Biol Chem, 2001 Aug 10. PMID 11346655
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_114647.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ABC2 homolog 7
    NP_190363.3
    • ABC2 homolog 7 (ATH7); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, transporter activity; INVOLVED IN: N-terminal protein myristoylation; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: ABC2 homolog 2 (TAIR:AT3G47740.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17629530..17633942
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339338.1 → NP_001327141.1  ABC2 homolog 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VDE4, A0A1I9LRE1

    2. NM_001339337.1 → NP_001327142.1  ABC2 homolog 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VDE4, A0A1I9LRE2

    3. NM_114647.4 → NP_190363.3  ABC2 homolog 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190363.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LPK0, Q9STT4
      UniProtKB/TrEMBL
      A0A654FDQ3
      Conserved Domains (4) summary
      cd03263
      Location:590 → 811
      ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
      COG1131
      Location:585 → 897
      CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
      pfam12698
      Location:247 → 488
      ABC2_membrane_3; ABC-2 family transporter protein
      cl00473
      Location:367 → 451
      BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LPK0.3

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