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    BIL4 Bax inhibitor-1 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825506, updated on 18-Sep-2024

    Summary

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    Official Symbol
    BIL4
    Official Full Name
    Bax inhibitor-1 family protein
    Primary source
    TAIR:AT3G63310
    Locus tag
    AT3G63310
    See related
    Araport:AT3G63310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtLFG2; BRZ-INSENSITIVE-LONG HYPOCOTYLS 4; LFG2; LIFEGUARD 2; MAA21.11
    Summary
    Mediates cell elongation in brassinosteroid signaling.
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    Genomic context

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    See BIL4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (23387718..23389038, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene NIMA-related kinase 4 Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene FORKED 1 Neighboring gene Protein phosphatase 2C family protein Neighboring gene kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chemical genetics reveal the novel transmembrane protein BIL4, which mediates plant cell elongation in brassinosteroid signaling. Yamagami A, et al. Biosci Biotechnol Biochem, 2009 Feb. PMID 19202280
    2. Evolutionarily conserved BIL4 suppresses the degradation of brassinosteroid receptor BRI1 and regulates cell elongation. Yamagami A, et al. Sci Rep, 2017 Jul 18. PMID 28720789, Free PMC Article
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results demonstrate that BIL4 regulates cell elongation and BR signaling via the regulation of BRI1 localization.
      Title: Evolutionarily conserved BIL4 suppresses the degradation of brassinosteroid receptor BRI1 and regulates cell elongation.
    2. BIL4 is a positive regulator of plant cell elongation via BR signaling. [BIL4]
      Title: Chemical genetics reveal the novel transmembrane protein BIL4, which mediates plant cell elongation in brassinosteroid signaling.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_116196.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glutamate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within brassinosteroid mediated signaling pathway IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within brassinosteroid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of plant organ morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within unidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Bax inhibitor-1 family protein
    NP_191890.1
    • BRZ-INSENSITIVE-LONG HYPOCOTYLS 4 (BIL4); CONTAINS InterPro DOMAIN/s: Inhibitor of apoptosis-promoting Bax1 related (InterPro:IPR006214); BEST Arabidopsis thaliana protein match is: Bax inhibitor-1 family protein (TAIR:AT1G03070.2); Has 5145 Blast hits to 5145 proteins in 1455 species: Archae - 0; Bacteria - 2761; Metazoa - 841; Fungi - 142; Plants - 239; Viruses - 82; Other Eukaryotes - 1080 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      23387718..23389038 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116196.3 → NP_191890.1  Bax inhibitor-1 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191890.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M1V9
      UniProtKB/TrEMBL
      A0A178VHV2, A0A5S9XQ36
      Conserved Domains (1) summary
      cl00473
      Location:22 → 225
      BI-1-like; BAX inhibitor (BI)-1/YccA-like protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M1V9.1

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