DFR dihydroflavonol 4-reductase [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DFR
Official Full Name: dihydroflavonol 4-reductase
Primary source: TAIR:AT5G42800
Locus tag: AT5G42800
See related: Araport:AT5G42800
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: dihydroflavonol 4-reductase; DIHYDROFLAVONOL 4-REDUCTASE; DIHYDROKAEMPFEROL 4-REDUCTASE; M318; MJB21.18; MJB21_18; TT3
Summary: dihydroflavonol reductase. Catalyzes the conversion of dihydroquercetin to leucocyanidin in the biosynthesis of anthocyanins. Not expressed in roots (qRT-PCR).
NEW: Try the new Gene table
Try the new Transcript table

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_123645.4

Function	Evidence Code	Pubs
enables dihydrokaempferol 4-reductase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables dihydrokaempferol 4-reductase activity	TAS Traceable Author Statement more info	PubMed
enables flavanone 4-reductase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in anthocyanin-containing compound biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within anthocyanin-containing compound biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within anthocyanin-containing compound biosynthetic process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in extrinsic component of endoplasmic reticulum membrane	TAS Traceable Author Statement more info	PubMed

NP_199094.1

dihydroflavonol 4-reductase (DFR); CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT2G45400.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).