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    GPT1 glucose 6-phosphate/phosphate translocator 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835570, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GPT1
    Official Full Name
    glucose 6-phosphate/phosphate translocator 1
    Primary source
    TAIR:AT5G54800
    Locus tag
    AT5G54800
    See related
    Araport:AT5G54800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS GLUCOSE 6-PHOSPHATE/PHOSPHATE TRANSLOCATOR 1; ATGPT1; glucose 6-phosphate/phosphate translocator 1
    Summary
    Encodes glucose6-Phosphate/phosphate transporter 1. Essential for pollen maturation and embryo sac development.
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    Genomic context

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    See GPT1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (22261134..22263936)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene CTD small phosphatase-like protein Neighboring gene tryptophan synthase beta-subunit 1 Neighboring gene F-box/RNI-like superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The plastidial glucose-6-phosphate/phosphate antiporter GPT1 is essential for morphogenesis in Arabidopsis embryos. Andriotis VM, et al. Plant J, 2010 Oct. PMID 20659277
    2. The Arabidopsis plastidic glucose 6-phosphate/phosphate translocator GPT1 is essential for pollen maturation and embryo sac development. Niewiadomski P, et al. Plant Cell, 2005 Mar. PMID 15722468, Free PMC Article
    3. The Arabidopsis Plastidial Glucose-6-Phosphate Transporter GPT1 is Dually Targeted to Peroxisomes via the Endoplasmic Reticulum. Baune MC, et al. Plant Cell, 2020 May. PMID 32111666, Free PMC Article
    4. Nematode-induced changes of transporter gene expression in Arabidopsis roots. Hammes UZ, et al. Mol Plant Microbe Interact, 2005 Dec. PMID 16478044
    5. A split-ubiquitin yeast two-hybrid screen to examine the substrate specificity of atToc159 and atToc132, two Arabidopsis chloroplast preprotein import receptors. Dutta S, et al. PLoS One, 2014. PMID 24736607, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Arabidopsis Plastidial Glucose-6-Phosphate Transporter GPT1 is Dually Targeted to Peroxisomes via the Endoplasmic Reticulum.
      Title: The Arabidopsis Plastidial Glucose-6-Phosphate Transporter GPT1 is Dually Targeted to Peroxisomes via the Endoplasmic Reticulum.
    2. Seed-specific AtGPT1 down-regulation results in abnormal morphogenesis and early embryo death.
      Title: The plastidial glucose-6-phosphate/phosphate antiporter GPT1 is essential for morphogenesis in Arabidopsis embryos.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    NM_124861.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables glucose-6-phosphate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphoglycerate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables triose-phosphate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo sac development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in glucose-6-phosphate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within lipid droplet organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phosphoenolpyruvate transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphoglycerate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to nematode HEP PubMed 
    involved_in triose phosphate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    glucose 6-phosphate/phosphate translocator 1
    NP_568812.1
    • glucose 6-phosphate/phosphate translocator 1 (GPT1); FUNCTIONS IN: antiporter activity, glucose-6-phosphate transmembrane transporter activity; INVOLVED IN: vacuole organization, pollen maturation, embryo sac development, response to nematode, lipid particle organization; LOCATED IN: integral to membrane, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tpt phosphate/phosphoenolpyruvate translocator (InterPro:IPR004696), Protein of unknown function DUF250 (InterPro:IPR004853); BEST Arabidopsis thaliana protein match is: glucose-6-phosphate/phosphate translocator 2 (TAIR:AT1G61800.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22261134..22263936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124861.5 → NP_568812.1  glucose 6-phosphate/phosphate translocator 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568812.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WW77, Q8LCH1, Q9FFU8, Q9M5A9
      UniProtKB/TrEMBL
      A0A178UL59, A0A5S9YE37
      Conserved Domains (1) summary
      pfam03151
      Location:95 → 384
      TPT; Triose-phosphate Transporter family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M5A9.1

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