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    skb1 protein arginine N-methyltransferase Skb1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540099, updated on 3-Dec-2024

    Summary

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    Official Symbol
    skb1
    Official Full Name
    protein arginine N-methyltransferase Skb1
    Primary source
    PomBase:SPBC16H5.11c
    Locus tag
    SPOM_SPBC16H5.11C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rmt5
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    Genomic context

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    See skb1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (2277255..2279624)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase Prp43 Neighboring gene ncRNA Neighboring gene alpha-1,2-mannosyltransferase Omh2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The highly conserved protein methyltransferase, Skb1, is a mediator of hyperosmotic stress response in the fission yeast Schizosaccharomyces pombe. Bao S, et al. J Biol Chem, 2001 May 4. PMID 11278267
    2. Control of cell polarity in fission yeast by association of Orb6p kinase with the highly conserved protein methyltransferase Skb1p. Wiley DJ, et al. J Biol Chem, 2003 Jul 4. PMID 12646585
    3. Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs. Gilbreth M, et al. Proc Natl Acad Sci U S A, 1998 Dec 8. PMID 9843966, Free PMC Article
    4. Direct activation of the fission yeast PAK Shk1 by the novel SH3 domain protein, Skb5. Yang P, et al. J Biol Chem, 1999 Dec 17. PMID 10593886
    5. The highly conserved skb1 gene encodes a protein that interacts with Shk1, a fission yeast Ste20/PAK homolog. Gilbreth M, et al. Proc Natl Acad Sci U S A, 1996 Nov 26. PMID 8943016, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Skb1 forms nodes by interacting with the novel protein Slf1, which is a limiting factor for node formation in cells. [Skb1 & Slf1]
      Title: Megadalton-node assembly by binding of Skb1 to the membrane anchor Slf1.
    2. Data show that the protein Skb1 interacted with both Cdr1 and the Cdr1 inhibitory target Wee1.
      Title: Compartmentalized nodes control mitotic entry signaling in fission yeast.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables histone arginine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in establishment or maintenance of bipolar cell polarity regulating cell shape IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in lateral cortical node assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein localization to lateral cortical node IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of establishment or maintenance of bipolar cell polarity regulating cell shape IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cdc42 GTPase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in cell cortex HDA PubMed 
    is_active_in cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of lateral cortical node IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein arginine N-methyltransferase Skb1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2277255..2279624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021844.3 → NP_595936.2  protein arginine N-methyltransferase Skb1 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O42946, P78963
      UniProtKB/TrEMBL
      A0AAN2HEP1
    Nucleotide Protein
    Heading Accession and Version

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