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    l(1)G0320 lethal (1) G0320 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326234, updated on 9-Dec-2024

    Summary

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    Official Symbol
    l(1)G0320provided by FlyBase
    Official Full Name
    lethal (1) G0320provided by FlyBase
    Primary source
    FLYBASE:FBgn0028327
    Locus tag
    Dmel_CG32701
    See related
    AllianceGenome:FB:FBgn0028327
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2994; CG32701; Dmel\CG32701
    Summary
    Located in endoplasmic reticulum and fusome. Is expressed in several structures, including adult brain cell body rind; embryonic/larval midgut primordium; epithelium; gut section; and mesoderm. Orthologous to human SSR1 (signal sequence receptor subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See l(1)G0320 in Genome Data Viewer
    Location:
    8E7-8E7; 1-28 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9551140..9553750, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9445173..9447783, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR42767 Neighboring gene Ribosomal protein S28b Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila sperm development and intercellular cytoplasm sharing through ring canals do not require an intact fusome. Kaufman RS, et al. Development, 2020 Nov 15. PMID 33033119, Free PMC Article
    2. New components of the Drosophila fusome suggest it plays novel roles in signaling and transport. Lighthouse DV, et al. Dev Biol, 2008 May 1. PMID 18355804, Free PMC Article
    3. Heat shock protein 83 (Hsp83) facilitates methoprene-tolerant (Met) nuclear import to modulate juvenile hormone signaling. He Q, et al. J Biol Chem, 2014 Oct 3. PMID 25122763, Free PMC Article
    4. Characterization of the Drosophila lipid droplet subproteome. Beller M, et al. Mol Cell Proteomics, 2006 Jun. PMID 16543254
    5. A P-insertion screen identifying novel X-linked essential genes in Drosophila. Bourbon HM, et al. Mech Dev, 2002 Jan. PMID 11744370

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fusome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    lethal (1) G0320
    Names
    CG32701-PA
    CG32701-PB
    l(1)G0320-PA
    l(1)G0320-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      9551140..9553750 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298129.1 → NP_001285058.1  lethal (1) G0320, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285058.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W335
      Conserved Domains (1) summary
      pfam03896
      Location:4 → 297
      TRAP_alpha; Translocon-associated protein (TRAP), alpha subunit

    2. NM_132339.3 → NP_572567.1  lethal (1) G0320, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572567.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W335
      Related
      FBpp0071307
      Conserved Domains (1) summary
      pfam03896
      Location:4 → 297
      TRAP_alpha; Translocon-associated protein (TRAP), alpha subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W335 Q9W335

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