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    CG31999 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43777, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG31999provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051999
    Locus tag
    Dmel_CG31999
    See related
    AllianceGenome:FB:FBgn0051999
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10323; CG11288; CT31491; CT7856; Dmel\CG31999
    Summary
    Predicted to enable calcium ion binding activity. Is expressed in larval muscle system; somatic muscle primordium; and visceral muscle primordium. Orthologous to several human genes including FBLN1 (fibulin 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31999 in Genome Data Viewer
    Location:
    102A8-102B1; 4-0 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 4 NC_004353.4 (215009..227748, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 4 NC_004353.3 (235635..248374, complement)

    Chromosome 4 - NC_004353.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Crk oncogene Neighboring gene pseudo Neighboring gene antisense RNA:CR46065 Neighboring gene yellow-h Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of PSMB5 as a genetic modifier of fragile X-associated tremor/ataxia syndrome. Kong HE, et al. Proc Natl Acad Sci U S A, 2022 May 31. PMID 35617426, Free PMC Article
    2. Molecular mapping of deletion breakpoints on chromosome 4 of Drosophila melanogaster. Podemski L, et al. Chromosoma, 2004 Jun. PMID 15185094
    3. Gene transposition as a cause of hybrid sterility in Drosophila. Masly JP, et al. Science, 2006 Sep 8. PMID 16960009
    4. Bioinformatic analysis suggests potential mechanisms underlying parasitoid venom evolution and function. Alvarado G, et al. Genomics, 2020 Mar. PMID 31247332
    5. The Genetic Architecture of Ovariole Number in Drosophila melanogaster: Genes with Major, Quantitative, and Pleiotropic Effects. Lobell AS, et al. G3 (Bethesda), 2017 Jul 5. PMID 28550012, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c217791-217647 mobile_element_type = transposon:INE-1{}4855
    • Loc: c219597-219149 mobile_element_type = transposon:F{}5373
    • Loc: c226986-226318 mobile_element_type = transposon:S{}1493

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31999-PA
    CG31999-PC
    fibrillin-like

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004353.4 Reference assembly

      Range
      215009..227748 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001297783.1 → NP_001284712.1  uncharacterized protein Dmel_CG31999, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284712.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V4B8
      Conserved Domains (5) summary
      smart00179
      Location:519 → 564
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:565 → 601
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:611 → 651
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:678 → 701
      cEGF; Complement Clr-like EGF-like
      cl00057
      Location:655 → 695
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    2. NM_166745.3 → NP_726551.2  uncharacterized protein Dmel_CG31999, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726551.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V4B8
      Related
      FBpp0088211
      Conserved Domains (5) summary
      smart00179
      Location:519 → 564
      EGF_CA; Calcium-binding EGF-like domain
      cd00054
      Location:565 → 601
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      pfam07645
      Location:611 → 651
      EGF_CA; Calcium-binding EGF domain
      pfam12662
      Location:678 → 701
      cEGF; Complement Clr-like EGF-like
      cl00057
      Location:655 → 695
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V4B8 Q9V4B8

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