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    Ctr9 Ctr9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38149, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ctr9provided by FlyBase
    Official Full Name
    Ctr9provided by FlyBase
    Primary source
    FLYBASE:FBgn0035205
    Locus tag
    Dmel_CG2469
    See related
    AllianceGenome:FB:FBgn0035205
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg2469; CG2469; dCtr9; Dmel\CG2469
    Summary
    Predicted to enable RNA polymerase II complex binding activity and SH2 domain binding activity. Involved in germ cell development; negative regulation of neuroblast proliferation; and regulation of gene expression. Predicted to be located in euchromatin. Predicted to be part of Cdc73/Paf1 complex. Is expressed in several structures, including CNS glial cell; embryonic/larval midgut primordium; ganglia; head epidermis primordium; and mesoderm. Orthologous to human CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Ctr9 in Genome Data Viewer
    Location:
    61F5-61F6; 3-0 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1307224..1311805)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1307224..1311805)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Rac1 Neighboring gene Acetyl-CoA acetyltransferase 2 Neighboring gene 5' nucleotidase A Neighboring gene sturkopf Neighboring gene HECT and RLD domain containing E3 ubiquitin ligase 4 Neighboring gene Myosin 61F Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables SH2 domain binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in euchromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    Ctr9
    Names
    CG2469-PA
    CG2469-PB
    Ctr9-PA
    Ctr9-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1307224..1311805
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176271.2NP_788449.1  Ctr9, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788449.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K0X3
      Related
      FBpp0072561
      Conserved Domains (4) summary
      sd00006
      Location:306334
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:344374
      TPR_1; Tetratricopeptide repeat
      pfam08424
      Location:400532
      NRDE-2; NRDE-2, necessary for RNA interference
      pfam13414
      Location:166228
      TPR_11; TPR repeat
    2. NM_176270.2NP_788448.1  Ctr9, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788448.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K0X3
      Related
      FBpp0072562
      Conserved Domains (4) summary
      sd00006
      Location:306334
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:344374
      TPR_1; Tetratricopeptide repeat
      pfam08424
      Location:400532
      NRDE-2; NRDE-2, necessary for RNA interference
      pfam13414
      Location:166228
      TPR_11; TPR repeat