onecut onecut [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: onecutprovided by FlyBase
Official Full Name: onecutprovided by FlyBase
Primary source: FLYBASE:FBgn0028996
Locus tag: Dmel_CG1922
See related: AllianceGenome:FB:FBgn0028996
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: A1; CG1922; Dmel\CG1922; Onecut
Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including ganglia; sense organ; sensory nervous system primordium; sensory neurons; and synaptic neuropil domain. Orthologous to human ONECUT1 (one cut homeobox 1); ONECUT2 (one cut homeobox 2); and ONECUT3 (one cut homeobox 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	4	NC_004353.4 (598555..607649, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	4	NC_004353.3 (619181..628275, complement)

Chromosome 4 - NC_004353.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain