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    CG33966 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3885642, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG33966provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0053966
    Locus tag
    Dmel_CG33966
    See related
    AllianceGenome:FB:FBgn0053966
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG1211; Dmel\CG33966
    Summary
    Predicted to enable lipid transfer activity and phosphatidylinositol bisphosphate binding activity. Predicted to be involved in intermembrane lipid transfer. Predicted to be located in late endosome. Orthologous to human TTPAL (alpha tocopherol transfer protein like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG33966 in Genome Data Viewer
    Location:
    61F4-61F4; 3-0 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (1234130..1235420)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (1234130..1235420)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene multiple wing hairs Neighboring gene Lysozyme S Neighboring gene long non-coding RNA:CR45747 Neighboring gene uncharacterized protein Neighboring gene galene Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genome-wide association study for nutritional indices in Drosophila. Unckless RL, et al. G3 (Bethesda), 2015 Jan 12. PMID 25583649, Free PMC Article
    2. Changes in Neuronal Signaling and Cell Stress Response Pathways are Associated with a Multigenic Response of Drosophila melanogaster to DDT Selection. Seong KM, et al. Genome Biol Evol, 2017 Dec 1. PMID 29211847, Free PMC Article
    3. A modERN resource: identification of Drosophila transcription factor candidate target genes using RNAi. Fisher WW, et al. Genetics, 2023 Apr 6. PMID 36652461, Free PMC Article
    4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables lipid transfer activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphatidylinositol bisphosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidylinositol bisphosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in intermembrane lipid transfer ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in late endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG33966-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      1234130..1235420
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038895.3 → NP_001033984.1  uncharacterized protein Dmel_CG33966 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033984.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E768, Q2MGL8
      Conserved Domains (2) summary
      smart01100
      Location:30 → 72
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      cd00170
      Location:96 → 252
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2MGL8 Q2MGL8

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