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    Snrpf small nuclear ribonucleoprotein polypeptide F [ Mus musculus (house mouse) ]

    Gene ID: 69878, updated on 9-Dec-2024

    Summary

    Official Symbol
    Snrpfprovided by MGI
    Official Full Name
    small nuclear ribonucleoprotein polypeptide Fprovided by MGI
    Primary source
    MGI:MGI:1917128
    See related
    Ensembl:ENSMUSG00000020018 AllianceGenome:MGI:1917128
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SMF; sm-F; snRNP-F; 2010013O18Rik
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to be located in cytosol and nucleus. Predicted to be part of several cellular components, including methylosome; nucleus; and pICln-Sm protein complex. Is expressed in central nervous system and sensory organ. Orthologous to human SNRPF (small nuclear ribonucleoprotein polypeptide F). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in liver E14 (RPKM 72.6), CNS E11.5 (RPKM 60.9) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Snrpf in Genome Data Viewer
    Location:
    10 C2; 10 48.57 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (93418891..93425520, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (93583029..93589658, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene histidine ammonia lyase Neighboring gene STARR-positive B cell enhancer ABC_E8360 Neighboring gene STARR-seq mESC enhancer starr_27586 Neighboring gene amidohydrolase domain containing 1 Neighboring gene coiled-coil domain containing 38 Neighboring gene STARR-positive B cell enhancer ABC_E6903 Neighboring gene RIKEN cDNA 4933408J17 gene Neighboring gene STARR-positive B cell enhancer ABC_E6904 Neighboring gene STARR-positive B cell enhancer ABC_E9800 Neighboring gene STARR-seq mESC enhancer starr_27587 Neighboring gene netrin 4 Neighboring gene ribosomal protein L29 pseudogene Neighboring gene predicted gene 15915

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in RNA splicing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in spliceosomal snRNP assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spliceosomal snRNP assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    part_of SMN-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SMN-Sm protein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U1 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U1 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U12-type spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of U12-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type catalytic step 2 spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type precatalytic spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U2-type spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U4 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U4 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U4/U6 x U5 tri-snRNP complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U4/U6 x U5 tri-snRNP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of U7 snRNP ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U7 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of methylosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of methylosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of pICln-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of pICln-Sm protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of pICln-Sm protein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of small nuclear ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small nuclear ribonucleoprotein F
    Names
    sm protein F

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027246.1NP_081522.1  small nuclear ribonucleoprotein F

      See identical proteins and their annotated locations for NP_081522.1

      Status: VALIDATED

      Source sequence(s)
      AK008240, BC066015, BQ748807
      Consensus CDS
      CCDS48672.1
      UniProtKB/Swiss-Prot
      P62307
      UniProtKB/TrEMBL
      Q3UX80, Q497K3
      Related
      ENSMUSP00000020203.7, ENSMUST00000020203.7
      Conserved Domains (1) summary
      cd01722
      Location:674
      Sm_F; Sm protein F

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      93418891..93425520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)