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    Slc35a5 solute carrier family 35, member A5 [ Mus musculus (house mouse) ]

    Gene ID: 74102, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Slc35a5provided by MGI
    Official Full Name
    solute carrier family 35, member A5provided by MGI
    Primary source
    MGI:MGI:1921352
    See related
    Ensembl:ENSMUSG00000022664 AllianceGenome:MGI:1921352
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D16Ertd450e; 1010001J06Rik; D730043G07Rik
    Summary
    Predicted to enable pyrimidine nucleotide-sugar transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in Golgi membrane. Is expressed in tail unsegmented mesenchyme and trunk somite. Orthologous to human SLC35A5 (solute carrier family 35 member A5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 9.5), CNS E18 (RPKM 6.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Slc35a5 in Genome Data Viewer
    Location:
    16 B5; 16 29.44 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (44959936..44979036, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (45139573..45158673, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53958 Neighboring gene coiled-coil domain containing 80 Neighboring gene STARR-positive B cell enhancer ABC_E1490 Neighboring gene autophagy related 3 Neighboring gene STARR-positive B cell enhancer ABC_E1925 Neighboring gene 40S ribosomal protein S24-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Microarray analysis of somitogenesis reveals novel targets of different WNT signaling pathways in the somitic mesoderm. Buttitta L, et al. Dev Biol, 2003 Jun 1. PMID 12781685
    2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    3. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pyrimidine nucleotide-sugar transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables pyrimidine nucleotide-sugar transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in pyrimidine nucleotide-sugar transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in Golgi membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    UDP-sugar transporter protein SLC35A5
    Names
    probable UDP-sugar transporter protein SLC35A5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001356453.1 → NP_001343382.1  UDP-sugar transporter protein SLC35A5 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC129601
      Conserved Domains (1) summary
      pfam04142
      Location:43 → 386
      Nuc_sug_transp; Nucleotide-sugar transporter

    2. NM_028756.4 → NP_083032.2  UDP-sugar transporter protein SLC35A5 isoform 1

      See identical proteins and their annotated locations for NP_083032.2

      Status: VALIDATED

      Source sequence(s)
      AK003124, AK033921, CJ075331
      Consensus CDS
      CCDS28193.1
      UniProtKB/Swiss-Prot
      Q921R7, Q9DC72
      Related
      ENSMUSP00000023344.4, ENSMUST00000023344.10
      Conserved Domains (1) summary
      pfam04142
      Location:43 → 387
      Nuc_sug_transp; Nucleotide-sugar transporter

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      44959936..44979036 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522647.5 → XP_006522710.1  UDP-sugar transporter protein SLC35A5 isoform X1

      Conserved Domains (1) summary
      pfam04142
      Location:46 → 403
      Nuc_sug_transp; Nucleotide-sugar transporter

    2. XM_006522648.5 → XP_006522711.1  UDP-sugar transporter protein SLC35A5 isoform X2

      Conserved Domains (1) summary
      pfam04142
      Location:46 → 402
      Nuc_sug_transp; Nucleotide-sugar transporter

    3. XM_036160154.1 → XP_036016047.1  UDP-sugar transporter protein SLC35A5 isoform X3

      UniProtKB/Swiss-Prot
      Q921R7, Q9DC72
      Conserved Domains (1) summary
      pfam04142
      Location:43 → 387
      Nuc_sug_transp; Nucleotide-sugar transporter

    4. XM_036160155.1 → XP_036016048.1  UDP-sugar transporter protein SLC35A5 isoform X4

      Conserved Domains (1) summary
      pfam04142
      Location:43 → 386
      Nuc_sug_transp; Nucleotide-sugar transporter
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q921R7.3 GenPept UniProtKB/Swiss-Prot:Q921R7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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