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    Lrrc42 leucine rich repeat containing 42 [ Mus musculus (house mouse) ]

    Gene ID: 77809, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Lrrc42provided by MGI
    Official Full Name
    leucine rich repeat containing 42provided by MGI
    Primary source
    MGI:MGI:1925059
    See related
    Ensembl:ENSMUSG00000028617 AllianceGenome:MGI:1925059
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A930011F22Rik
    Summary
    Is expressed in cranium; jaw; tail dorsal root ganglion; and ventral grey horn. Orthologous to human LRRC42 (leucine rich repeat containing 42). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 16.7), limb E14.5 (RPKM 15.6) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Lrrc42 in Genome Data Viewer
    Location:
    4 C7; 4 50.18 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (107090711..107110730, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (107233514..107253533, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 59 Neighboring gene low density lipoprotein receptor class A domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E4642 Neighboring gene intraflagellar transport 25 Neighboring gene Yip1 domain family, member 1 Neighboring gene deiodinase, iodothyronine, type I

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 42

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029985.2 → NP_084261.1  leucine-rich repeat-containing protein 42

      See identical proteins and their annotated locations for NP_084261.1

      Status: VALIDATED

      Source sequence(s)
      BC027203, BX632859, CJ174174
      Consensus CDS
      CCDS18434.1
      UniProtKB/Swiss-Prot
      Q3TE62, Q8R2U7, Q9CTP9
      Related
      ENSMUSP00000030360.5, ENSMUST00000030360.11
      Conserved Domains (2) summary
      cd00116
      Location:167 → 272
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00034
      Location:150 → 174
      LRR_AMN1; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      107090711..107110730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164551.1 → XP_036020444.1  leucine-rich repeat-containing protein 42 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8R2U7.1 GenPept UniProtKB/Swiss-Prot:Q8R2U7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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