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    GPX2 glutathione peroxidase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817715, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GPX2
    Official Full Name
    glutathione peroxidase 2
    Primary source
    TAIR:AT2G31570
    Locus tag
    AT2G31570
    See related
    Araport:AT2G31570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATGPX2; GLUTATHIONE PEROXIDASE; glutathione peroxidase 2; T9H9.9; T9H9_9
    Summary
    glutathione peroxidase GPx
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    Genomic context

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    See GPX2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (13437974..13439923, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene SecY protein transport family protein Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene SGNH hydrolase-type esterase superfamily protein Neighboring gene signal transducer/transcription protein, putative (DUF1685) Neighboring gene ncRNA Neighboring gene tRNAHis guanylyltransferase Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis DJ-1a protein confers stress protection through cytosolic SOD activation. Xu XM, et al. J Cell Sci, 2010 May 15. PMID 20406884
    2. Glutathione peroxidase genes in Arabidopsis are ubiquitous and regulated by abiotic stresses through diverse signaling pathways. Rodriguez Milla MA, et al. Plant J, 2003 Dec. PMID 14617062
    3. Identification of kinase substrates by bimolecular complementation assays. Pusch S, et al. Plant J, 2012 Apr. PMID 22098373
    4. Identification of multiple salicylic acid-binding proteins using two high throughput screens. Manohar M, et al. Front Plant Sci, 2014. PMID 25628632, Free PMC Article
    5. VH1/BRL2 receptor-like kinase interacts with vascular-specific adaptor proteins VIT and VIK to influence leaf venation. Ceserani T, et al. Plant J, 2009 Mar. PMID 19000166, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_128714.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glutathione peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables salicylic acid binding HDA PubMed 
    Process Evidence Code Pubs
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in peroxisome HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    glutathione peroxidase 2
    NP_180715.1
    • glutathione peroxidase 2 (GPX2); FUNCTIONS IN: glutathione peroxidase activity; INVOLVED IN: oxidation reduction, response to oxidative stress; LOCATED IN: cytosol; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like fold (InterPro:IPR012336), Glutathione peroxidase (InterPro:IPR000889); BEST Arabidopsis thaliana protein match is: glutathione peroxidase 7 (TAIR:AT4G31870.1); Has 7463 Blast hits to 7462 proteins in 1754 species: Archae - 2; Bacteria - 3597; Metazoa - 796; Fungi - 210; Plants - 383; Viruses - 8; Other Eukaryotes - 2467 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13437974..13439923 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128714.4 → NP_180715.1  glutathione peroxidase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180715.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04922
      UniProtKB/TrEMBL
      A0A178VYF3, A0A5S9X2Y3
      Conserved Domains (1) summary
      PLN02412
      Location:1 → 167
      PLN02412; probable glutathione peroxidase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04922.1

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