U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    GLX2-5 glyoxalase 2-5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817693, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GLX2-5
    Official Full Name
    glyoxalase 2-5
    Primary source
    TAIR:AT2G31350
    Locus tag
    AT2G31350
    See related
    Araport:AT2G31350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    glyoxalase 2-5; T28P16.16; T28P16_16
    Summary
    Encodes a mitochondrial glyoxalase 2 that can accommodate a number of different metal centers and with the predominant metal center being Fe(III)Zn(II).
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GLX2-5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (13368070..13371097)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene embryo defective 1381 Neighboring gene uncharacterized protein Neighboring gene 16:0delta9 desaturase 2 Neighboring gene Basic-leucine zipper (bZIP) transcription factor family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structural studies on a mitochondrial glyoxalase II. Marasinghe GP, et al. J Biol Chem, 2005 Dec 9. PMID 16227621, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    NM_128692.5
    NM_179835.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydroxyacylglutathione hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hydroxyacylglutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    glyoxalase 2-5
    NP_180693.1
    • glyoxalase 2-5 (GLX2-5); CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279), Hydroxyacylglutathione hydrolase (InterPro:IPR017782); BEST Arabidopsis thaliana protein match is: glyoxalase 2-4 (TAIR:AT1G06130.1); Has 16142 Blast hits to 16141 proteins in 2537 species: Archae - 414; Bacteria - 10534; Metazoa - 488; Fungi - 336; Plants - 226; Viruses - 0; Other Eukaryotes - 4144 (source: NCBI BLink).
    NP_850166.1
    • glyoxalase 2-5 (GLX2-5); CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279), Hydroxyacylglutathione hydrolase (InterPro:IPR017782); BEST Arabidopsis thaliana protein match is: glyoxalase 2-4 (TAIR:AT1G06130.2); Has 16139 Blast hits to 16138 proteins in 2537 species: Archae - 414; Bacteria - 10534; Metazoa - 489; Fungi - 336; Plants - 226; Viruses - 0; Other Eukaryotes - 4140 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13368070..13371097
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001336327.1 → NP_001324089.1  glyoxalase 2-5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AZ54

    2. NM_128692.5 → NP_180693.1  glyoxalase 2-5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180693.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3EBQ9, Q9SID3
      UniProtKB/TrEMBL
      A0A5S9X317, A0A654EYY2, A0A7G2EFI8
      Conserved Domains (1) summary
      PLN02398
      Location:1 → 324
      PLN02398; hydroxyacylglutathione hydrolase

    3. NM_179835.1 → NP_850166.1  glyoxalase 2-5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850166.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2EFI8
      Conserved Domains (3) summary
      PLN02398
      Location:1 → 323
      PLN02398; hydroxyacylglutathione hydrolase
      pfam16123
      Location:239 → 321
      HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
      cd07723
      Location:75 → 238
      hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SID3.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.