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    HMGA high mobility group A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838055, updated on 18-Sep-2024

    Summary

    Official Symbol
    HMGA
    Official Full Name
    high mobility group A
    Primary source
    TAIR:AT1G14900
    Locus tag
    AT1G14900
    See related
    Araport:AT1G14900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10B6.31; F10B6_31; high mobility group A
    Summary
    Encodes a protein belonging to the subgroup of HMGA (high mobility group A) proteins that interact with A/T-rich stretches of DNA.
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    Genomic context

    See HMGA in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (5138116..5139467, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene PLANT CADMIUM RESISTANCE 1 Neighboring gene Plant invertase/pectin methylesterase inhibitor superfamily protein Neighboring gene ENTH/ANTH/VHS superfamily protein Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_101359.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in nucleosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
     
    colocalizes_with chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    high mobility group A
    NP_172943.1
    • high mobility group A (HMGA); FUNCTIONS IN: DNA binding; INVOLVED IN: regulation of transcription, DNA-dependent, nucleosome assembly; LOCATED IN: cytosol, nuclear chromatin, nucleus; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), A.T hook-like (InterPro:IPR020478), AT hook, DNA-binding motif (InterPro:IPR017956), High mobility group, HMG-I/HMG-Y (InterPro:IPR000116), Histone H1/H5 (InterPro:IPR005818); BEST Arabidopsis thaliana protein match is: winged-helix DNA-binding transcription factor family protein (TAIR:AT3G18035.1); Has 1377 Blast hits to 1228 proteins in 223 species: Archae - 0; Bacteria - 119; Metazoa - 428; Fungi - 179; Plants - 544; Viruses - 9; Other Eukaryotes - 98 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5138116..5139467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101359.4NP_172943.1  high mobility group A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172943.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P92954, Q43386, Q8LGC1
      UniProtKB/TrEMBL
      A0A178WDX9, A0A5S9UIR2, A0A7G2DVW6
      Conserved Domains (1) summary
      smart00526
      Location:2285
      H15; Domain in histone families 1 and 5