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    RDH2 rhodanese homologue 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838216, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RDH2
    Official Full Name
    rhodanese homologue 2
    Primary source
    TAIR:AT1G16460
    Locus tag
    AT1G16460
    See related
    Araport:AT1G16460
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA MERCAPTOPYRUVATE SULFURTRANSFERASE 2; ATMST2; ATRDH2; F3O9.26; F3O9_26; MERCAPTOPYRUVATE SULFURTRANSFERASE; MERCAPTOPYRUVATE SULFURTRANSFERASE 2; MST2; rhodanese homologue 2; ST2; STR2; SULFURTRANSFERASE 2
    Summary
    encodes a cytoplasmic thiosulfate:cyanide sulfurtransferase, activity of which increased the rhodanese activity of transgenic yeast. Can also act as a mercaptopyruvate sulfurtransferase.
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    Genomic context

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    See RDH2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (5619545..5622674, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene tRNA-Arg Neighboring gene proteasome subunit PAB1 Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Solution structure of a single-domain thiosulfate sulfurtransferase from Arabidopsis thaliana. Cornilescu G, et al. Protein Sci, 2006 Dec. PMID 17088324, Free PMC Article
    2. Sulfurtransferases 1 and 2 play essential roles in embryo and seed development in Arabidopsis thaliana. Mao G, et al. J Biol Chem, 2011 Mar 4. PMID 21189252, Free PMC Article
    3. Plant mercaptopyruvate sulfurtransferases: molecular cloning, subcellular localization and enzymatic activities. Nakamura T, et al. Eur J Biochem, 2000 Sep. PMID 10951223
    4. Evidence for the existence of rhodanese (thiosulfate:cyanide sulfurtransferase) in plants: preliminary characterization of two rhodanese cDNAs from Arabidopsis thaliana. Hatzfeld Y, et al. FEBS Lett, 2000 Mar 24. PMID 10734224
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The incomplete penetrance of str1 embryo/seed phenotype is a result of functional STR2
      Title: Sulfurtransferases 1 and 2 play essential roles in embryo and seed development in Arabidopsis thaliana.
    2. Three-dimensional structure of the product of Arabidopsis thaliana gene At5g66040.1.
      Title: Solution structure of a single-domain thiosulfate sulfurtransferase from Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001035979.1
    NM_001198083.1
    NM_001332227.1
    NM_179344.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-mercaptopyruvate sulfurtransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables thiosulfate sulfurtransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables thiosulfate sulfurtransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiosulfate sulfurtransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in embryo development ending in seed dormancy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    rhodanese homologue 2
    NP_001031056.1
    • rhodanese homologue 2 (RDH2); FUNCTIONS IN: 3-mercaptopyruvate sulfurtransferase activity, thiosulfate sulfurtransferase activity; INVOLVED IN: sulfate transport, aging; LOCATED IN: cytosol, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rhodanese-like (InterPro:IPR001763), Thiosulphate sulfurtransferase, conserved site (InterPro:IPR001307); BEST Arabidopsis thaliana protein match is: mercaptopyruvate sulfurtransferase 1 (TAIR:AT1G79230.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001185012.1
    • rhodanese homologue 2 (RDH2); FUNCTIONS IN: 3-mercaptopyruvate sulfurtransferase activity, thiosulfate sulfurtransferase activity; INVOLVED IN: sulfate transport, aging; LOCATED IN: cytosol, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rhodanese-like (InterPro:IPR001763), Thiosulphate sulfurtransferase, conserved site (InterPro:IPR001307); BEST Arabidopsis thaliana protein match is: mercaptopyruvate sulfurtransferase 1 (TAIR:AT1G79230.1).
    NP_563998.1
    • rhodanese homologue 2 (RDH2); FUNCTIONS IN: 3-mercaptopyruvate sulfurtransferase activity, thiosulfate sulfurtransferase activity; INVOLVED IN: sulfate transport, aging; LOCATED IN: cytosol, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rhodanese-like (InterPro:IPR001763), Thiosulphate sulfurtransferase, conserved site (InterPro:IPR001307); BEST Arabidopsis thaliana protein match is: mercaptopyruvate sulfurtransferase 1 (TAIR:AT1G79230.1); Has 6167 Blast hits to 6142 proteins in 1437 species: Archae - 162; Bacteria - 3582; Metazoa - 248; Fungi - 148; Plants - 95; Viruses - 0; Other Eukaryotes - 1932 (source: NCBI BLink).
    NP_849675.1
    • rhodanese homologue 2 (RDH2); FUNCTIONS IN: 3-mercaptopyruvate sulfurtransferase activity, thiosulfate sulfurtransferase activity; INVOLVED IN: sulfate transport, aging; LOCATED IN: cytosol, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rhodanese-like (InterPro:IPR001763), Thiosulphate sulfurtransferase, conserved site (InterPro:IPR001307); BEST Arabidopsis thaliana protein match is: mercaptopyruvate sulfurtransferase 1 (TAIR:AT1G79230.1); Has 6167 Blast hits to 6142 proteins in 1437 species: Archae - 162; Bacteria - 3582; Metazoa - 248; Fungi - 148; Plants - 95; Viruses - 0; Other Eukaryotes - 1932 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      5619545..5622674 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332226.1 → NP_001322506.1  rhodanese homologue 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AU81, A0A5S9UQ58, A0A654EAI3

    2. NM_101511.6 → NP_563998.1  rhodanese homologue 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563998.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W5B2, A0A7G2DTN7
      Conserved Domains (1) summary
      PLN02723
      Location:1 → 318
      PLN02723; 3-mercaptopyruvate sulfurtransferase

    3. NM_001198083.1 → NP_001185012.1  rhodanese homologue 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185012.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W5B2, A0A7G2DTN7
      Conserved Domains (1) summary
      PLN02723
      Location:1 → 318
      PLN02723; 3-mercaptopyruvate sulfurtransferase

    4. NM_001035979.1 → NP_001031056.1  rhodanese homologue 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031056.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W5B2, A0A7G2DTN7
      Conserved Domains (1) summary
      PLN02723
      Location:1 → 318
      PLN02723; 3-mercaptopyruvate sulfurtransferase

    5. NM_001332227.1 → NP_001322507.1  rhodanese homologue 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AU99, A0A5S9UQ58, A0A654EAI3
      Conserved Domains (1) summary
      PLN02723
      Location:1 → 263
      PLN02723; 3-mercaptopyruvate sulfurtransferase

    6. NM_179344.2 → NP_849675.1  rhodanese homologue 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849675.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WQ03, Q24JL3, Q9M4F7, Q9S7Y9, Q9SA45
      UniProtKB/TrEMBL
      A0A7G2DTN7
      Conserved Domains (3) summary
      PLN02723
      Location:25 → 342
      PLN02723; 3-mercaptopyruvate sulfurtransferase
      cd01448
      Location:45 → 168
      TST_Repeat_1; Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it ...
      cd01449
      Location:216 → 330
      TST_Repeat_2; Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q24JL3.1

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