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    FHY1 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844318, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FHY1
    Official Full Name
    Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
    Primary source
    TAIR:AT1G79790
    Locus tag
    AT1G79790
    See related
    Araport:AT1G79790
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis thaliana chloroplast FMN hydrolase 1; AtcpFHy1; F20B17.21; F20B17_21; flavin mononucleotide hydrolase 1
    Summary
    Encodes a chloroplast-localized FMN hydrolase that whose phosphatase activity is FMN-specific.
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    Genomic context

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    See FHY1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (30016671..30018234, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene downstream target of AGL15-4 Neighboring gene CASP-like protein (DUF1677) Neighboring gene Uncharacterized protein family (UPF0497) Neighboring gene early nodulin-like protein 7 Neighboring gene Pex2/Pex12 N-terminal domain-containing protein / zinc finger (C3HC4-type RING finger) family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An FMN hydrolase of the haloacid dehalogenase superfamily is active in plant chloroplasts. Rawat R, et al. J Biol Chem, 2011 Dec 9. PMID 22002057, Free PMC Article
    2. Identification and characterization of the missing phosphatase on the riboflavin biosynthesis pathway in Arabidopsis thaliana. Sa N, et al. Plant J, 2016 Dec. PMID 27490826
    3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001334921.1
    NM_001334923.1
    NM_106628.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables FMN hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
    NP_001319420.1
    • Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; FUNCTIONS IN: hydrolase activity; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: HAD-superfamily hydrolase, subfamily IA, variant 3 (InterPro:IPR006402); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_565221.1
    • Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; FUNCTIONS IN: hydrolase activity; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: HAD-superfamily hydrolase, subfamily IA, variant 3 (InterPro:IPR006402); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30016671..30018234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001334922.1 → NP_001323208.1  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AWB4

    2. NM_001334921.1 → NP_001319420.1  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WHD4, A0A5S9WVU7, F4HQA8
      Conserved Domains (1) summary
      cl21460
      Location:50 → 258
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    3. NM_106628.3 → NP_565221.1  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565221.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84VZ1, Q8LCB6, Q9MA00
      UniProtKB/TrEMBL
      A0A178WFR0, A0A5S9WVU7
      Conserved Domains (1) summary
      cl21460
      Location:50 → 233
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    4. NM_001334923.1 → NP_001323207.1  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AWF1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84VZ1.1

    Gene LinkOut

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