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    TIM50 Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842040, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TIM50
    Official Full Name
    Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
    Primary source
    TAIR:AT1G55900
    Locus tag
    AT1G55900
    See related
    Araport:AT1G55900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    emb1860; EMB1860; embryo defective 1860; F14J16.15; F14J16_15
    Summary
    component of a translocase in the mitochondrial inner membrane
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    Genomic context

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    See TIM50 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (20903053..20905853)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene Pyridoxal-5'-phosphate-dependent enzyme family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene zinc transporter 11 precursor Neighboring gene zinc ion binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis mitochondrial protein TIM50 affects hypocotyl cell elongation through intracellular ATP level. Kumar S, et al. Plant Sci, 2012 Feb. PMID 22195596
    2. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
    3. The hydrophobic proteome of mitochondrial membranes from Arabidopsis cell suspensions. Brugière S, et al. Phytochemistry, 2004 Jun. PMID 15276431
    4. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001198317.1
    NM_104467.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
    NP_001185246.1
    • TIM50; CONTAINS InterPro DOMAIN/s: NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: Haloacid dehalogenase-like hydrolase (HAD) superfamily protein (TAIR:AT1G29780.1).
    NP_175986.2
    • TIM50; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: mitochondrion, mitochondrial inner membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: Haloacid dehalogenase-like hydrolase (HAD) superfamily protein (TAIR:AT1G29780.1); Has 2137 Blast hits to 2133 proteins in 243 species: Archae - 0; Bacteria - 8; Metazoa - 726; Fungi - 412; Plants - 369; Viruses - 0; Other Eukaryotes - 622 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20903053..20905853
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198317.1 → NP_001185246.1  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185246.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WKS8, A0A5S9WQA4, F4I3H1
      Conserved Domains (1) summary
      pfam03031
      Location:191 → 338
      NIF; NLI interacting factor-like phosphatase

    2. NM_104467.5 → NP_175986.2  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175986.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56X01, Q8VYE2, Q9LG22
      UniProtKB/TrEMBL
      A0A178WKS8, A0A5S9WQA4
      Conserved Domains (1) summary
      pfam03031
      Location:191 → 338
      NIF; NLI interacting factor-like phosphatase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VYE2.1

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