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    GC5 golgin Putative 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844322, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GC5
    Official Full Name
    golgin Putative 5
    Primary source
    TAIR:AT1G79830
    Locus tag
    AT1G79830
    See related
    Araport:AT1G79830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19K16.21; F19K16_21; golgin candidate 5
    Summary
    This gene is predicted to encode a protein that functions as a Golgi apparatus structural component known as a golgin in mammals and yeast. A fluorescently-tagged version of GC5 co-localizes with Golgi markers, and this localization appears to be replicated using the C-terminal (139 aa) portion of the protein. The C-terminal portion of the protein can also specifically interact with two members of the Rab family of GTPases (RabH1b and RabH1c).
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    Genomic context

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    See GC5 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    21
    Sequence:
    Chromosome: 1; NC_003070.9 (30027569..30033907, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Pex2/Pex12 N-terminal domain-containing protein / zinc finger (C3HC4-type RING finger) family protein Neighboring gene Major facilitator superfamily protein Neighboring gene ncRNA Neighboring gene HD-ZIP IV family of homeobox-leucine zipper protein with lipid-binding START domain-containing protein Neighboring gene ncRNA Neighboring gene RHO guanyl-nucleotide exchange factor 12 Neighboring gene ribosomal protein S17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fluorescence lifetime imaging of interactions between Golgi tethering factors and small GTPases in plants. Osterrieder A, et al. Traffic, 2009 Aug. PMID 19490533
    2. Localization and domain characterization of Arabidopsis golgin candidates. Latijnhouwers M, et al. J Exp Bot, 2007. PMID 18182439
    3. Analysis of the Arabidopsis nuclear proteome and its response to cold stress. Bae MS, et al. Plant J, 2003 Dec. PMID 14617066
    4. A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis. Waidmann S, et al. Plant Cell, 2014 Nov. PMID 25387881, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001124150.1
    NM_001198512.1
    NM_001198513.2
    NM_001334925.1
    NM_106632.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    golgin Putative 5
    NP_001117622.1
    • golgin candidate 5 (GC5); FUNCTIONS IN: protein binding; INVOLVED IN: biological_process unknown; LOCATED IN: Golgi apparatus, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TATA element modulatory factor 1 DNA binding (InterPro:IPR022092), TATA element modulatory factor 1 TATA binding (InterPro:IPR022091); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001185441.1
    • golgin candidate 5 (GC5); FUNCTIONS IN: protein binding; INVOLVED IN: biological_process unknown; LOCATED IN: Golgi apparatus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TATA element modulatory factor 1 DNA binding (InterPro:IPR022092), TATA element modulatory factor 1 TATA binding (InterPro:IPR022091).
    NP_001185442.1
    • golgin candidate 5 (GC5); FUNCTIONS IN: protein binding; INVOLVED IN: biological_process unknown; LOCATED IN: Golgi apparatus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TATA element modulatory factor 1 DNA binding (InterPro:IPR022092), TATA element modulatory factor 1 TATA binding (InterPro:IPR022091).
    NP_178101.3
    • golgin candidate 5 (GC5); FUNCTIONS IN: protein binding; INVOLVED IN: biological_process unknown; LOCATED IN: Golgi apparatus, nucleus, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TATA element modulatory factor 1 DNA binding (InterPro:IPR022092), TATA element modulatory factor 1 TATA binding (InterPro:IPR022091); Has 167116 Blast hits to 92088 proteins in 3687 species: Archae - 2004; Bacteria - 38214; Metazoa - 68462; Fungi - 14168; Plants - 9575; Viruses - 617; Other Eukaryotes - 34076 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30027569..30033907 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198513.2 → NP_001185442.1  golgin Putative 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185442.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WVL7, Q56X06, Q9CA88
      UniProtKB/TrEMBL
      A0A178WIG2, A0A654EVL8
      Conserved Domains (4) summary
      PLN02939
      Location:268 → 498
      PLN02939; transferase, transferring glycosyl groups
      PRK08581
      Location:21 → 255
      PRK08581; amidase domain-containing protein
      TIGR02169
      Location:401 → 817
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam12325
      Location:855 → 951
      TMF_TATA_bd; TATA element modulatory factor 1 TATA binding

    2. NM_106632.4 → NP_178101.3  golgin Putative 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178101.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WVL7, Q56X06, Q9CA88
      UniProtKB/TrEMBL
      A0A178WIG2, A0A654EVL8
      Conserved Domains (4) summary
      PLN02939
      Location:268 → 498
      PLN02939; transferase, transferring glycosyl groups
      PRK08581
      Location:21 → 255
      PRK08581; amidase domain-containing protein
      TIGR02169
      Location:401 → 817
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam12325
      Location:855 → 951
      TMF_TATA_bd; TATA element modulatory factor 1 TATA binding

    3. NM_001334925.1 → NP_001321438.1  golgin Putative 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AQY7, A0A654EVL8

    4. NM_001198512.1 → NP_001185441.1  golgin Putative 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185441.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EVL8, F4HQB9
      Conserved Domains (2) summary
      pfam12325
      Location:859 → 971
      TMF_TATA_bd; TATA element modulatory factor 1 TATA binding
      pfam12329
      Location:432 → 505
      TMF_DNA_bd; TATA element modulatory factor 1 DNA binding

    5. NM_001124150.1 → NP_001117622.1  golgin Putative 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117622.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WVL7, Q56X06, Q9CA88
      UniProtKB/TrEMBL
      A0A178WIG2, A0A654EVL8
      Conserved Domains (4) summary
      PLN02939
      Location:268 → 498
      PLN02939; transferase, transferring glycosyl groups
      PRK08581
      Location:21 → 255
      PRK08581; amidase domain-containing protein
      TIGR02169
      Location:401 → 817
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam12325
      Location:855 → 951
      TMF_TATA_bd; TATA element modulatory factor 1 TATA binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WVL7.1

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