ACS2 1-amino-cyclopropane-1-carboxylate synthase 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: ACS2
Official Full Name: 1-amino-cyclopropane-1-carboxylate synthase 2
Primary source: TAIR:AT1G01480
Locus tag: AT1G01480
See related: Araport:AT1G01480
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: 1-amino-cyclopropane-1-carboxylate synthase 2; 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE; AT-ACC2; EC 4.4.1.14; F22L4.4; F22L4_4; S-ADENOSYL-L-METHIONINE METHYLTHIOADENOSINE-LYASE
Summary: a member of the 1-aminocyclopropane-1-carboxylate (ACC) synthase (S-adenosyl-L-methionine methylthioadenosine-lyase, EC 4.4.1.14) gene family, isolated from a flower-specific cDNA library.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See ACS2 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 4

Sequence:: Chromosome: 1; NC_003070.9 (175706..178406)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Arabidopsis WRKY71 regulates ethylene-mediated leaf senescence by directly activating EIN2, ORE1 and ACS2 genes.
Title: Arabidopsis WRKY71 regulates ethylene-mediated leaf senescence by directly activating EIN2, ORE1 and ACS2 genes.
ACS2 and ACS6 are the main isoforms involved in Cd-induced ethylene production.
Title: Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression.
direct binding of WRKY33 to the W-boxes in the promoters of ACS2 and ACS6 genes in vivo, suggesting that WRKY33 is directly involved in the activation of ACS2 and ACS6 expression downstream of MPK3/MPK6 cascade in response to pathogen invasion
Title: Dual-level regulation of ACC synthase activity by MPK3/MPK6 cascade and its downstream WRKY transcription factor during ethylene induction in Arabidopsis.
ACS2 and ACS6 are involved in Botrytis-induced ethylene production.
Title: Mitogen-activated protein kinase 3 and 6 regulate Botrytis cinerea-induced ethylene production in Arabidopsis.
Data showed that the expression of ACS2 is induced during hypoxia.
Title: Differential expression of genes encoding 1-aminocyclopropane-1-carboxylate synthase in Arabidopsis during hypoxia.

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

MASC_STS15319 (e-PCR)
- UniSTS:258793

NM_100030.4

Supported by ESTs:

NM_179241.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables 1-aminocyclopropane-1-carboxylate synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within 1-aminocyclopropane-1-carboxylate biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in ethylene biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ethylene biosynthetic process	TAS Traceable Author Statement more info	PubMed
involved_in response to water deprivation	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info

General protein information

Go to the top of the page Help

Preferred Names: 1-amino-cyclopropane-1-carboxylate synthase 2

NP_171655.1

1-amino-cyclopropane-1-carboxylate synthase 2 (ACS2); CONTAINS InterPro DOMAIN/s: 1-aminocyclopropane-1-carboxylate synthase (InterPro:IPR001176), Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: ACC synthase 1 (TAIR:AT3G61510.1); Has 30194 Blast hits to 30192 proteins in 2936 species: Archae - 881; Bacteria - 20730; Metazoa - 650; Fungi - 807; Plants - 1338; Viruses - 0; Other Eukaryotes - 5788 (source: NCBI BLink).

NP_849572.1

1-amino-cyclopropane-1-carboxylate synthase 2 (ACS2); CONTAINS InterPro DOMAIN/s: 1-aminocyclopropane-1-carboxylate synthase (InterPro:IPR001176), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: ACC synthase 1 (TAIR:AT3G61510.1); Has 28365 Blast hits to 28364 proteins in 2923 species: Archae - 821; Bacteria - 19365; Metazoa - 634; Fungi - 793; Plants - 1286; Viruses - 0; Other Eukaryotes - 5466 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

175706..178406

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_100030.4 → NP_171655.1 1-amino-cyclopropane-1-carboxylate synthase 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_171655.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q06402, Q941E7

UniProtKB/TrEMBL

A0A178WMN2, A0A654E5W3

Conserved Domains (1) summary

PLN02376
Location:1 → 496

PLN02376; 1-aminocyclopropane-1-carboxylate synthase
NM_179241.1 → NP_849572.1 1-amino-cyclopropane-1-carboxylate synthase 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_849572.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q06402

Conserved Domains (1) summary

cd00609
Location:4 → 328

AAT_like; Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine ...