Amino acid kinase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Full Name: Amino acid kinase family protein
Primary source: TAIR:AT3G18680
Locus tag: AT3G18680
See related: Araport:AT3G18680
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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Genomic context

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See in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 7

Sequence:: Chromosome: 3; NC_003074.8 (6427403..6429692)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PUMPKIN is a homomultimeric, plastid-localized protein that forms in vivo RNA-containing megadalton-sized complexes and catalyzes the ATP-dependent conversion of UMP to UDP in vitro with properties characteristic of known essential eubacterial UMP kinases.
Title: PUMPKIN, the Sole Plastid UMP Kinase, Associates with Group II Introns and Alters Their Metabolism.
The nuclear encoded protein Dpt1 is essential for retaining photosynthetic activity in higher plant chloroplasts and involved in post-transcriptional steps of psaA/B transcript accumulation. [Dpt1]
Title: A protein related to prokaryotic UMP kinases is involved in psaA/B transcript accumulation in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001338352.1

Supported by ESTs:

NM_112754.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables RNA binding	IPI Inferred from Physical Interaction more info	PubMed
enables UMP kinase activity	IDA Inferred from Direct Assay more info	PubMed
enables sequence-specific mRNA binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in 'de novo' CTP biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chloroplast RNA processing	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within_positive_effect chloroplast RNA processing	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within chloroplast organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within_positive_effect regulation of photosynthesis, light reaction	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to light stimulus	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Amino acid kinase family protein

NP_188498.1

Amino acid kinase family protein; FUNCTIONS IN: uridylate kinase activity, UMP kinase activity; INVOLVED IN: cellular amino acid biosynthetic process, pyrimidine nucleotide biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aspartate/glutamate/uridylate kinase (InterPro:IPR001048), Uridylate kinase, bacteria (InterPro:IPR015963); BEST Arabidopsis thaliana protein match is: aspartate/glutamate/uridylate kinase family protein (TAIR:AT3G10030.1); Has 10647 Blast hits to 10647 proteins in 2814 species: Archae - 356; Bacteria - 8071; Metazoa - 2; Fungi - 40; Plants - 182; Viruses - 0; Other Eukaryotes - 1996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

6427403..6429692

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_112754.3 → NP_188498.1 Amino acid kinase family protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_188498.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LSA9

UniProtKB/TrEMBL

A0A5S9XDE5, A0A654F9I2

Conserved Domains (1) summary

cd04254
Location:97 → 328

AAK_UMPK-PyrH-Ec; UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and ...
NM_001338352.1 → NP_001327269.1 Amino acid kinase family protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1I9LRT3, A0A5S9XDE5