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    APG3 Peptide chain release factor 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825466, updated on 18-Sep-2024

    Summary

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    Official Symbol
    APG3
    Official Full Name
    Peptide chain release factor 1
    Primary source
    TAIR:AT3G62910
    Locus tag
    AT3G62910
    See related
    Araport:AT3G62910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ALBINO AND PALE GREEN; Arabidopsis thaliana chloroplast RF1; AtcpRF1; chloroplast ribosome release factor 1; cpRF1
    Summary
    Encodes a plastid-localized ribosome release factor 1 that is essential in chloroplast development. Pale green, albino mutant seedlings arrest early in seedling development.
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    Genomic context

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    See APG3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Sequence:
    Chromosome: 3; NC_003074.8 (23257404..23260480, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene CW-type Zinc Finger Neighboring gene zinc metalloproteinase aureolysin Neighboring gene Thioredoxin superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chloroplast ribosome release factor 1 (AtcpRF1) is essential for chloroplast development. Motohashi R, et al. Plant Mol Biol, 2007 Jul. PMID 17450416
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_116156.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables translation release factor activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables translation release factor activity, codon specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast organization NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within plastid translation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within thylakoid membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within translational termination IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Peptide chain release factor 1
    NP_191850.2
    • ALBINO AND PALE GREEN (APG3); FUNCTIONS IN: translation release factor activity, codon specific, translation release factor activity; INVOLVED IN: translational termination, chloroplast organization; LOCATED IN: chloroplast, cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptide chain release factor 1 (InterPro:IPR004373), Class I peptide chain release factor (InterPro:IPR000352), Peptide chain release factor (InterPro:IPR005139); BEST Arabidopsis thaliana protein match is: Peptide chain release factor 1 (TAIR:AT2G47020.1); Has 17224 Blast hits to 17222 proteins in 2820 species: Archae - 0; Bacteria - 10525; Metazoa - 262; Fungi - 197; Plants - 224; Viruses - 13; Other Eukaryotes - 6003 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      23257404..23260480 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116156.5 → NP_191850.2  Peptide chain release factor 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191850.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RX79, Q9LYD0
      UniProtKB/TrEMBL
      A0A178VJK1, A0A5S9XNH7, A0A7G2EW88
      Conserved Domains (1) summary
      PRK00591
      Location:54 → 412
      prfA; peptide chain release factor 1; Validated
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RX79.1

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