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    cpHsc70-2 chloroplast heat shock protein 70-2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835054, updated on 18-Sep-2024

    Summary

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    Official Symbol
    cpHsc70-2
    Official Full Name
    chloroplast heat shock protein 70-2
    Primary source
    TAIR:AT5G49910
    Locus tag
    AT5G49910
    See related
    Araport:AT5G49910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    chloroplast heat shock protein 70-2; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 70-7; HSC70-7; K9P8.5; K9P8_5
    Summary
    Stromal heat shock protein involved in protein import into chloroplast.
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    Genomic context

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    See cpHsc70-2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (20303334..20306469)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene mitotic checkpoint family protein Neighboring gene chloride channel C Neighboring gene Beta-glucosidase, GBA2 type family protein Neighboring gene Octicosapeptide/Phox/Bem1p family protein Neighboring gene ncRNA Neighboring gene zinc knuckle (CCHC-type) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis stromal 70-kD heat shock proteins are essential for plant development and important for thermotolerance of germinating seeds. Su PH, et al. Plant Physiol, 2008 Mar. PMID 18192441, Free PMC Article
    2. Stromal Hsp70 is important for protein translocation into pea and Arabidopsis chloroplasts. Su PH, et al. Plant Cell, 2010 May. PMID 20484004, Free PMC Article
    3. Comprehensive expression profile analysis of the Arabidopsis Hsp70 gene family. Sung DY, et al. Plant Physiol, 2001 Jun. PMID 11402207, Free PMC Article
    4. The Extra-Pathway Interactome of the TCA Cycle: Expected and Unexpected Metabolic Interactions. Zhang Y, et al. Plant Physiol, 2018 Jul. PMID 29794018, Free PMC Article
    5. High light response of the thylakoid proteome in arabidopsis wild type and the ascorbate-deficient mutant vtc2-2. A comparative proteomics study. Giacomelli L, et al. Plant Physiol, 2006 Jun. PMID 16648217, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. redundant but also distinct functions compared to cpHsc70-1
      Title: Arabidopsis stromal 70-kD heat shock proteins are essential for plant development and important for thermotolerance of germinating seeds.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_124369.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP-dependent protein folding chaperone IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein folding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to chloroplast IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in intracellular anatomical structure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in plastid HDA PubMed 
    located_in plastid stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid stroma TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in thylakoid HDA PubMed 

    General protein information

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    Preferred Names
    chloroplast heat shock protein 70-2
    NP_199802.1
    • chloroplast heat shock protein 70-2 (CPHSC70-2EAT SHOCK PROTEIN 70-2); FUNCTIONS IN: protein binding; INVOLVED IN: protein folding, response to cadmium ion, protein targeting to chloroplast, response to heat; LOCATED IN: in 6 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Chaperone DnaK (InterPro:IPR012725), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: chloroplast heat shock protein 70-1 (TAIR:AT4G24280.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      20303334..20306469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124369.4 → NP_199802.1  chloroplast heat shock protein 70-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199802.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RXD1, Q9LTX9, Q9M637
      UniProtKB/TrEMBL
      A0A178UDJ5
      Conserved Domains (2) summary
      cd10234
      Location:78 → 453
      HSPA9-Ssq1-like_NBD; Nucleotide-binding domain of human HSPA9 and similar proteins
      PLN03184
      Location:41 → 716
      PLN03184; chloroplast Hsp70; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LTX9.1

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