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    ACBP5 acyl-CoA binding protein 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832825, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ACBP5
    Official Full Name
    acyl-CoA binding protein 5
    Primary source
    TAIR:AT5G27630
    Locus tag
    AT5G27630
    See related
    Araport:AT5G27630
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    acyl-CoA binding protein 5; AtACBP5; F15A18.90; F15A18_90
    Summary
    Acyl-CoA binding protein with high affinity for oleoyl-CoA. Expressed in all plant organs. Involved in fatty acid transport.
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    Genomic context

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    See ACBP5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    17
    Sequence:
    Chromosome: 5; NC_003076.8 (9775854..9781002)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene protein ALWAYS EARLY 1 Neighboring gene cyclin H;1 Neighboring gene translation initiation factor 3B1 Neighboring gene Tudor/PWWP/MBT superfamily protein Neighboring gene ncRNA Neighboring gene Trypsin family protein with PDZ domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Kelch-motif containing acyl-CoA binding proteins AtACBP4 and AtACBP5 are differentially expressed and function in floral lipid metabolism. Ye ZW, et al. Plant Mol Biol, 2017 Jan. PMID 27826761
    2. Light-regulated Arabidopsis ACBP4 and ACBP5 encode cytosolic acyl-CoA-binding proteins that bind phosphatidylcholine and oleoyl-CoA ester. Xiao S, et al. Plant Physiol Biochem, 2009 Oct. PMID 19589686
    3. Arabidopsis acyl-CoA-binding proteins ACBP4 and ACBP5 are subcellularly localized to the cytosol and ACBP4 depletion affects membrane lipid composition. Xiao S, et al. Plant Mol Biol, 2008 Dec. PMID 18773301, Free PMC Article
    4. Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development. Hsiao AS, et al. Biosci Rep, 2014 Dec 23. PMID 25423293, Free PMC Article
    5. The Arabidopsis cytosolic Acyl-CoA-binding proteins play combinatory roles in pollen development. Hsiao AS, et al. Plant Cell Physiol, 2015 Feb. PMID 25395473

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtACBP4 and AtACBP5 both function in floral lipidic metabolism and play complementary roles in Arabidopsis microspore-to-pollen development.
      Title: Kelch-motif containing acyl-CoA binding proteins AtACBP4 and AtACBP5 are differentially expressed and function in floral lipid metabolism.
    2. The roles of cytosolic AtACBP4, 5 and 6 in floral development were addressed in this study.
      Title: The Arabidopsis cytosolic Acyl-CoA-binding proteins play combinatory roles in pollen development.
    3. Data indicate that the acyl-CoA-binding proteins acbp4acbp5acbp6 mutant showed the lightest seed weight and highest sensitivity to abscisic acid during germination.
      Title: Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development.
    4. Data suggest that light-regulated ACBP4 and ACBP5 are potential candidates for the intracellular transport of oleoyl-CoA ester exported from the chloroplast to the endoplasmic reticulum for the biosynthesis of non-plastidial membrane lipids.
      Title: Light-regulated Arabidopsis ACBP4 and ACBP5 encode cytosolic acyl-CoA-binding proteins that bind phosphatidylcholine and oleoyl-CoA ester.
    5. ACBP4 and ACBP5 are available in the cytosol to bind and transfer cytosolic oleoyl-CoA esters
      Title: Arabidopsis acyl-CoA-binding proteins ACBP4 and ACBP5 are subcellularly localized to the cytosol and ACBP4 depletion affects membrane lipid composition.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001344023.1
    NM_122645.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to light stimulus TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    acyl-CoA binding protein 5
    NP_198115.2
    • acyl-CoA binding protein 5 (ACBP5); FUNCTIONS IN: acyl-CoA binding; INVOLVED IN: lipid transport; LOCATED IN: cytosol; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 2 (InterPro:IPR011498), Acyl-CoA-binding protein, ACBP (InterPro:IPR000582), Kelch-type beta propeller (InterPro:IPR015915), FERM/acyl-CoA-binding protein, 3-helical bundle (InterPro:IPR014352); BEST Arabidopsis thaliana protein match is: acyl-CoA binding protein 4 (TAIR:AT3G05420.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      9775854..9781002
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344021.1 → NP_001331944.1  acyl-CoA binding protein 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BFD3, A0A5S9Y8U4

    2. NM_001344022.1 → NP_001331946.1  acyl-CoA binding protein 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BFF0, A0A5S9Y8U4

    3. NM_122645.5 → NP_198115.2  acyl-CoA binding protein 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_198115.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8RWD9
      UniProtKB/TrEMBL
      A0A654G4N9
      Conserved Domains (5) summary
      sd00038
      Location:296 → 343
      Kelch; KELCH repeat [structural motif]
      pfam00887
      Location:15 → 103
      ACBP; Acyl CoA binding protein
      pfam09304
      Location:533 → 618
      Cortex-I_coil; Cortexillin I, coiled coil
      pfam13415
      Location:305 → 355
      Kelch_3; Galactose oxidase, central domain
      pfam13854
      Location:182 → 220
      Kelch_5; Kelch motif

    4. NM_001344023.1 → NP_001331945.1  acyl-CoA binding protein 5 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BFG3, A0A654G4N9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RWD9.1

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