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    ASA2 anthranilate synthase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817519, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ASA2
    Official Full Name
    anthranilate synthase 2
    Primary source
    TAIR:AT2G29690
    Locus tag
    AT2G29690
    See related
    Araport:AT2G29690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    anthranilate synthase 2; ATHANSYNAB; T27A16.21; T27A16_21
    Summary
    Encode a functional anthranilate synthase protein. Expressed at a constitutive basal level. Expression was not induced by wounding nor bacterial pathogen infiltration. Involved in aromatic amino acid biosynthesis.
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    Genomic context

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    See ASA2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (12693734..12697091)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene cell division control 6 Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene pleckstrin homologue 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two anthranilate synthase genes in Arabidopsis: defense-related regulation of the tryptophan pathway. Niyogi KK, et al. Plant Cell, 1992 Jun. PMID 1392592, Free PMC Article
    2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001336222.1
    NM_128523.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables anthranilate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables anthranilate synthase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within aromatic amino acid family biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tryptophan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tryptophan biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of anthranilate synthase complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    anthranilate synthase 2
    NP_180530.1
    • anthranilate synthase 2 (ASA2); FUNCTIONS IN: anthranilate synthase activity; INVOLVED IN: tryptophan biosynthetic process, aromatic amino acid family biosynthetic process; LOCATED IN: chloroplast, anthranilate synthase complex; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Anthranilate synthase component I, N-terminal (InterPro:IPR006805), Chorismate binding, C-terminal (InterPro:IPR015890), ADC synthase (InterPro:IPR005801), Anthranilate synthase component I (InterPro:IPR019999), Anthranilate synthase component I, PabB-like (InterPro:IPR005256); BEST Arabidopsis thaliana protein match is: anthranilate synthase alpha subunit 1 (TAIR:AT5G05730.1); Has 16475 Blast hits to 16472 proteins in 2614 species: Archae - 246; Bacteria - 11051; Metazoa - 5; Fungi - 314; Plants - 193; Viruses - 0; Other Eukaryotes - 4666 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12693734..12697091
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128523.5 → NP_180530.1  anthranilate synthase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180530.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P32069, Q56XS1
      UniProtKB/TrEMBL
      A0A178VSK8, A0A5S9X2M2
      Conserved Domains (3) summary
      PLN02445
      Location:85 → 607
      PLN02445; anthranilate synthase component I
      pfam00425
      Location:320 → 590
      Chorismate_bind; chorismate binding enzyme
      pfam04715
      Location:104 → 258
      Anth_synt_I_N; Anthranilate synthase component I, N terminal region

    2. NM_001336222.1 → NP_001324956.1  anthranilate synthase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VSK8, A0A1P8B1S3, A0A5S9X2M2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32069.1

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