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    DRG1 developmentally regulated G-protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838320, updated on 18-Sep-2024

    Summary

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    Official Symbol
    DRG1
    Official Full Name
    developmentally regulated G-protein 1
    Primary source
    TAIR:AT1G17470
    Locus tag
    AT1G17470
    See related
    Araport:AT1G17470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATDRG; ATDRG1; developmentally regulated G-protein 1; F28G4.4
    Summary
    Encodes a member of the DRG (developmentally regulated G-protein) family expressed throughout the plant, with highest expression in actively growing tissues. Has GTPase activity.
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    Genomic context

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    See DRG1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (6002888..6006410)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ELF4-like 4 Neighboring gene TRF-like 3 Neighboring gene IQ-domain 7 Neighboring gene epidermal patterning factor-like protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and identification of phosphatidic acid targets from plants. Testerink C, et al. Plant J, 2004 Aug. PMID 15272872
    2. Characterization of ATDRG1, a member of a new class of GTP-binding proteins in plants. Etheridge N, et al. Plant Mol Biol, 1999 Apr. PMID 10380799
    3. Biochemical characterization of Arabidopsis developmentally regulated G-proteins (DRGs). O'Connell A, et al. Protein Expr Purif, 2009 Oct. PMID 19460440
    4. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    5. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084086.1
    NM_101609.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GDP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTPase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidic acid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasmic vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    developmentally regulated G-protein 1
    NP_001077555.1
    • developmentally regulated G-protein 1 (DRG1); CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), TGS (InterPro:IPR004095), GTP1/OBG (InterPro:IPR006073), GTP1/OBG, conserved site (InterPro:IPR006074), GTP-binding protein, HSR1-related (InterPro:IPR002917); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT1G72660.3); Has 20324 Blast hits to 20306 proteins in 2951 species: Archae - 770; Bacteria - 13313; Metazoa - 856; Fungi - 587; Plants - 375; Viruses - 0; Other Eukaryotes - 4423 (source: NCBI BLink).
    NP_173190.1
    • developmentally regulated G-protein 1 (DRG1); CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), TGS (InterPro:IPR004095), GTP1/OBG (InterPro:IPR006073), GTP1/OBG, conserved site (InterPro:IPR006074), GTP-binding protein, HSR1-related (InterPro:IPR002917); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT1G72660.3); Has 20324 Blast hits to 20306 proteins in 2951 species: Archae - 770; Bacteria - 13313; Metazoa - 856; Fungi - 587; Plants - 375; Viruses - 0; Other Eukaryotes - 4423 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6002888..6006410
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101609.4 → NP_173190.1  developmentally regulated G-protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173190.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04174, Q94K69, Q9LNQ8, Q9LQK0
      UniProtKB/TrEMBL
      A0A178W426, A0A5S9UX14, A0A654EZ50
      Conserved Domains (1) summary
      COG1163
      Location:1 → 367
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]

    2. NM_001084086.1 → NP_001077555.1  developmentally regulated G-protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077555.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04174, Q94K69, Q9LNQ8, Q9LQK0
      UniProtKB/TrEMBL
      A0A178W426, A0A5S9UX14, A0A654EZ50
      Conserved Domains (1) summary
      COG1163
      Location:1 → 367
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LQK0.1

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