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    ESP3 RNA helicase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840143, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ESP3
    Official Full Name
    RNA helicase family protein
    Primary source
    TAIR:AT1G32490
    Locus tag
    AT1G32490
    See related
    Araport:AT1G32490
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMB2733; EMBRYO DEFECTIVE 2733; ENHANCED SILENCING PHENOTYPE 3; F5D14.27; F5D14_27
    Summary
    Encodes a homolog of the yeast PRP2 protein, one of four related DEAH RNA helicases identified as essential cofactors for RNA splicing.
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    Genomic context

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    See ESP3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    28
    Sequence:
    Chromosome: 1; NC_003070.9 (11742006..11749788, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Single hybrid motif superfamily protein Neighboring gene isocitrate dehydrogenase IV Neighboring gene non-intrinsic ABC protein 6 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis GSM1 is involved in ABI4-regulated ABA signaling under high-glucose condition in early seedling growth. Zheng M, et al. Plant Sci, 2019 Oct. PMID 31481206
    2. A temperature-sensitive allele of a putative mRNA splicing helicase down-regulates many cell wall genes and causes radial swelling in Arabidopsis thaliana. Howles PA, et al. Plant Mol Biol, 2016 May. PMID 27008640
    3. Molecular profiling of stomatal meristemoids reveals new component of asymmetric cell division and commonalities among stem cell populations in Arabidopsis. Pillitteri LJ, et al. Plant Cell, 2011 Sep. PMID 21963668, Free PMC Article
    4. Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis. Herr AJ, et al. Proc Natl Acad Sci U S A, 2006 Oct 10. PMID 17008405, Free PMC Article
    5. Recruitment of the NineTeen Complex to the activated spliceosome requires AtPRMT5. Deng X, et al. Proc Natl Acad Sci U S A, 2016 May 10. PMID 27114555, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. GSM1 plays an important role in the ABI4-regulated Glc-ABA signaling cascade during Arabidopsis early seedling growth. [GSM1]
      Title: Arabidopsis GSM1 is involved in ABI4-regulated ABA signaling under high-glucose condition in early seedling growth.
    2. These data showed that ESP3 is a helicase involved in mRNA splicing.
      Title: A temperature-sensitive allele of a putative mRNA splicing helicase down-regulates many cell wall genes and causes radial swelling in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001198198.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within RNA splicing NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within regulatory ncRNA-mediated post-transcriptional gene silencing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RNA helicase family protein
    NP_001185127.1
    • ENHANCED SILENCING PHENOTYPE 3 (ESP3); FUNCTIONS IN: helicase activity, ATP-dependent RNA helicase activity, ATP binding, ATP-dependent helicase activity, nucleic acid binding; INVOLVED IN: RNA splicing, posttranscriptional gene silencing by RNA, embryo development ending in seed dormancy; LOCATED IN: endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helicase-associated domain (InterPro:IPR007502), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), Domain of unknown function DUF1605 (InterPro:IPR011709), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: helicase domain-containing protein (TAIR:AT2G35340.1).
    NP_174527.2
    • ENHANCED SILENCING PHENOTYPE 3 (ESP3); FUNCTIONS IN: helicase activity, ATP-dependent RNA helicase activity, ATP binding, ATP-dependent helicase activity, nucleic acid binding; INVOLVED IN: RNA splicing, posttranscriptional gene silencing by RNA, embryo development ending in seed dormancy; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helicase-associated domain (InterPro:IPR007502), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), Domain of unknown function DUF1605 (InterPro:IPR011709), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: helicase domain-containing protein (TAIR:AT2G35340.1); Has 34186 Blast hits to 25955 proteins in 2213 species: Archae - 99; Bacteria - 5536; Metazoa - 12019; Fungi - 3203; Plants - 1844; Viruses - 1463; Other Eukaryotes - 10022 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      11742006..11749788 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102984.5 → NP_174527.2  RNA helicase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174527.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8VY00, Q9LQK8
      UniProtKB/TrEMBL
      A0A178W3A5, A0A7G2DUU5
      Conserved Domains (2) summary
      PTZ00121
      Location:112 → 391
      PTZ00121; MAEBL; Provisional
      COG1643
      Location:365 → 1034
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]

    2. NM_001198198.1 → NP_001185127.1  RNA helicase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185127.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2DUU5, F4IE90
      Conserved Domains (5) summary
      smart00490
      Location:620 → 722
      HELICc; helicase superfamily c-terminal domain
      smart00847
      Location:792 → 877
      HA2; Helicase associated domain (HA2) Add an annotation
      COG1643
      Location:355 → 1024
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd00046
      Location:411 → 549
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam07717
      Location:901 → 1011
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VY00.1

    Gene LinkOut

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