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    GC6 golgin Putative 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822375, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GC6
    Official Full Name
    golgin Putative 6
    Primary source
    TAIR:AT3G27530
    Locus tag
    AT3G27530
    See related
    Araport:AT3G27530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    golgin candidate 6; MAG4; MAIGO 4
    Summary
    This gene is predicted to encode a protein that functions as a Golgi apparatus structural component known as a golgin in mammals and yeast. A fluorescently-tagged version of GC6 co-localizes with Golgi markers, and this localization appears to be replicated using the C-terminal (225 aa) portion of the protein.
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    Genomic context

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    See GC6 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    20
    Sequence:
    Chromosome: 3; NC_003074.8 (10193477..10200046, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Cysteine/Histidine-rich C1 domain family protein Neighboring gene cryptic loci regulator Neighboring gene beta-1,4-N-acetylglucosaminyltransferase family protein Neighboring gene RNA-binding CRS1 / YhbY (CRM) domain protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MAG4/Atp115 is a golgi-localized tethering factor that mediates efficient anterograde transport in Arabidopsis. Takahashi H, et al. Plant Cell Physiol, 2010 Oct. PMID 20837504
    2. Localization and domain characterization of Arabidopsis golgin candidates. Latijnhouwers M, et al. J Exp Bot, 2007. PMID 18182439
    3. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MAG4 functions in the transport of storage protein precursors from the ER to the Golgi complex during seed maturation.
      Title: MAG4/Atp115 is a golgi-localized tethering factor that mediates efficient anterograde transport in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_113669.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within post-embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein exit from endoplasmic reticulum IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in vesicle fusion with Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi stack IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    golgin Putative 6
    NP_566820.1
    • golgin candidate 6 (GC6); FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, Golgi vesicle transport, vesicle fusion with Golgi apparatus; LOCATED IN: cytosol, Golgi apparatus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Uso1/p115 like vesicle tethering protein, C-terminal (InterPro:IPR006955), Armadillo-type fold (InterPro:IPR016024), Uso1/p115 like vesicle tethering protein, head region (InterPro:IPR006953); Has 8674 Blast hits to 6651 proteins in 794 species: Archae - 167; Bacteria - 1154; Metazoa - 4083; Fungi - 784; Plants - 382; Viruses - 31; Other Eukaryotes - 2073 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      10193477..10200046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113669.3 → NP_566820.1  golgin Putative 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566820.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B0F9L4, Q940C3, Q9LT59
      UniProtKB/TrEMBL
      A0A5S9XGC3, A0A654FBH6
      Conserved Domains (3) summary
      pfam04869
      Location:359 → 683
      Uso1_p115_head; Uso1 / p115 like vesicle tethering protein, head region
      pfam04871
      Location:788 → 903
      Uso1_p115_C; Uso1 / p115 like vesicle tethering protein, C terminal region
      pfam09730
      Location:704 → 837
      BicD; Microtubule-associated protein Bicaudal-D
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B0F9L4.2

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