U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Amino acid dehydrogenase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820409, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Full Name
    Amino acid dehydrogenase family protein
    Primary source
    TAIR:AT3G12290
    Locus tag
    AT3G12290
    See related
    Araport:AT3G12290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (3919463..3921519)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene LYR family of Fe/S cluster biogenesis protein Neighboring gene ncRNA Neighboring gene protein arginine methyltransferase 3 Neighboring gene retinoblastoma-related 1 Neighboring gene cilia/flagella-associated protein Neighboring gene uncharacterized protein Neighboring gene FKBP-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene FKBP-type peptidyl-prolyl cis-trans isomerase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. MTHFD1 controls DNA methylation in Arabidopsis. Groth M, et al. Nat Commun, 2016 Jun 13. PMID 27291711, Free PMC Article
    2. Proteomic analysis of the 26S proteasome reveals its direct interaction with transit peptides of plastid protein precursors for their degradation. Sako K, et al. J Proteome Res, 2014 Jul 3. PMID 24846764
    3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_112065.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables methenyltetrahydrofolate cyclohydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in tetrahydrofolate interconversion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tetrahydrofolate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Amino acid dehydrogenase family protein
    NP_187837.1
    • Amino acid dehydrogenase family protein; FUNCTIONS IN: binding, catalytic activity; INVOLVED IN: folic acid and derivative biosynthetic process, metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (InterPro:IPR020631), Tetrahydrofolate dehydrogenase/cyclohydrolase (InterPro:IPR000672), NAD(P)-binding domain (InterPro:IPR016040), Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site (InterPro:IPR020867), Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (InterPro:IPR020630); BEST Arabidopsis thaliana protein match is: Amino acid dehydrogenase family protein (TAIR:AT4G00620.1); Has 9969 Blast hits to 9964 proteins in 2781 species: Archae - 105; Bacteria - 5648; Metazoa - 394; Fungi - 308; Plants - 157; Viruses - 0; Other Eukaryotes - 3357 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3919463..3921519
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112065.3 → NP_187837.1  Amino acid dehydrogenase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187837.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LEA3, Q9LHH7
      UniProtKB/TrEMBL
      A0A178VD60, A0A5S9XBC0
      Conserved Domains (3) summary
      cd01080
      Location:122 → 294
      NAD_bind_m-THF_DH_Cyclohyd; NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
      PLN02516
      Location:1 → 299
      PLN02516; methylenetetrahydrofolate dehydrogenase (NADP+)
      pfam00763
      Location:11 → 127
      THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LHH7.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools