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    CYP86A1 cytochrome P450, family 86, subfamily A, polypeptide 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836003, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYP86A1
    Official Full Name
    cytochrome P450, family 86, subfamily A, polypeptide 1
    Primary source
    TAIR:AT5G58860
    Locus tag
    AT5G58860
    See related
    Araport:AT5G58860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''cytochrome P450; CYP86; cytochrome P450; family 86; HORST; hydroxylase of root suberized tissue; K19M22.14; K19M22_14; polypeptide 1; polypeptide 1''; subfamily A
    Summary
    Encodes a member of the CYP86A subfamily of cytochrome p450 genes. Expressed significantly only in root tissue.
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    Genomic context

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    See CYP86A1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (23765791..23768111, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Subtilase family protein Neighboring gene myb domain protein 119 Neighboring gene FTSH protease 9 Neighboring gene LRR protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid omega-hydroxylase involved in suberin monomer biosynthesis. Höfer R, et al. J Exp Bot, 2008. PMID 18544608, Free PMC Article
    2. Identification of acyltransferases required for cutin biosynthesis and production of cutin with suberin-like monomers. Li Y, et al. Proc Natl Acad Sci U S A, 2007 Nov 13. PMID 17991776, Free PMC Article
    3. Differential expression and evolution of the Arabidopsis CYP86A subfamily. Duan H, et al. Plant Physiol, 2005 Mar. PMID 15709153, Free PMC Article
    4. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. cytochrome P450 fatty acid omega-hydroxylase CYP86A1 (At5g58860) was identified as a key enzyme for aliphatic root suberin biosynthesis in Arabidopsis.
      Title: The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid omega-hydroxylase involved in suberin monomer biosynthesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_125276.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables alkane 1-monooxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables long-chain fatty acid omega-hydroxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within fatty acid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within suberin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plant-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    cytochrome P450, family 86, subfamily A, polypeptide 1
    NP_200694.1
    • ''cytochrome P450, family 86, subfamily A, polypeptide 1'' (CYP86A1); FUNCTIONS IN: alkane 1-monooxygenase activity, oxygen binding; INVOLVED IN: fatty acid metabolic process, suberin biosynthetic process; LOCATED IN: vacuole; EXPRESSED IN: hypocotyl, root; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 86, subfamily A, polypeptide 2 (TAIR:AT4G00360.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      23765791..23768111 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125276.3 → NP_200694.1  cytochrome P450, family 86, subfamily A, polypeptide 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200694.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48422, Q8RXG6, Q9FIM3
      UniProtKB/TrEMBL
      A0A178UBQ8, A0A5S9YFB0, A0A654GCB6
      Conserved Domains (1) summary
      cd11064
      Location:70 → 501
      CYP86A; cytochrome P450 family 86, subfamily A
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48422.2

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