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    PLDBETA1 phospholipase D beta 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818802, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PLDBETA1
    Official Full Name
    phospholipase D beta 1
    Primary source
    TAIR:AT2G42010
    Locus tag
    AT2G42010
    See related
    Araport:AT2G42010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    PHOSPHOLIPASE D; phospholipase D beta 1; PLDBETA; T6D20.10; T6D20_10
    Summary
    phospholipase D (PLDbeta)
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    Genomic context

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    See PLDBETA1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (17532813..17538628, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene plant EC metallothionein family protein Neighboring gene Transmembrane amino acid transporter family protein Neighboring gene tRNA-Ser Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis phospholipase Dβ1 modulates defense responses to bacterial and fungal pathogens. Zhao J, et al. New Phytol, 2013 Jul. PMID 23577648, Free PMC Article
    2. Evidence for and characterization of Ca2+ binding to the catalytic region of Arabidopsis thaliana phospholipase Dbeta. Pappan K, et al. J Biol Chem, 2004 Nov 12. PMID 15356005
    3. Differential expression of genes encoding Arabidopsis phospholipases after challenge with virulent or avirulent Pseudomonas isolates. de Torres Zabela M, et al. Mol Plant Microbe Interact, 2002 Aug. PMID 12182338
    4. Molecular cloning and functional analysis of polyphosphoinositide-dependent phospholipase D, PLDbeta, from Arabidopsis. Pappan K, et al. J Biol Chem, 1997 Mar 14. PMID 9054397
    5. Molecular heterogeneity of phospholipase D (PLD). Cloning of PLDgamma and regulation of plant PLDgamma, -beta, and -alpha by polyphosphoinositides and calcium. Qin W, et al. J Biol Chem, 1997 Nov 7. PMID 9353280

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Phospholipase Dbeta1 modulates defense responses to bacterial and fungal pathogens in Arabidopsis
      Title: Arabidopsis phospholipase Dβ1 modulates defense responses to bacterial and fungal pathogens.
    2. Results demonstrate the effects of calcium- and lipid-binding properties of the C2 and catalytic domains of plant phospholipase D (PLD) and provide insight into the mechanism by which calcium regulates PLD activity.
      Title: Evidence for and characterization of Ca2+ binding to the catalytic region of Arabidopsis thaliana phospholipase Dbeta.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001336948.1
    NM_129765.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables N-acylphosphatidylethanolamine-specific phospholipase D activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-4,5-bisphosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phospholipase D activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phospholipase D activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phospholipase D activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phospholipase D activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    phospholipase D beta 1
    NP_565963.2
    • phospholipase D beta 1 (PLDBETA1); FUNCTIONS IN: phospholipase D activity, protein binding, phosphatidylinositol-4,5-bisphosphate binding; INVOLVED IN: response to cadmium ion, defense response to bacterium, incompatible interaction; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), Phospholipase D (InterPro:IPR015679), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase D/Transphosphatidylase (InterPro:IPR001736), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: phospholipase D beta 2 (TAIR:AT4G00240.1); Has 42228 Blast hits to 24253 proteins in 1246 species: Archae - 34; Bacteria - 3967; Metazoa - 15807; Fungi - 8808; Plants - 7882; Viruses - 972; Other Eukaryotes - 4758 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17532813..17538628 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129765.4 → NP_565963.2  phospholipase D beta 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565963.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4ILZ0, P93733, P93745
      UniProtKB/TrEMBL
      A0A178VSC5
      Conserved Domains (6) summary
      cd04015
      Location:267 → 416
      C2_plant_PLD; C2 domain present in plant phospholipase D (PLD)
      PLN03008
      Location:263 → 1082
      PLN03008; Phospholipase D delta
      pfam12357
      Location:1006 → 1074
      PLD_C; Phospholipase D C terminal
      pfam15991
      Location:66 → 233
      G_path_suppress; G-protein pathway suppressor
      cl15239
      Location:768 → 979
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins
      cl23807
      Location:66 → 138
      WWbp; WW-domain ligand protein

    2. NM_001336948.1 → NP_001324696.1  phospholipase D beta 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VSC5, A0A1P8B0W4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P93733.4

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