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    LPR1 Cupredoxin superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838909, updated on 18-Sep-2024

    Summary

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    Official Symbol
    LPR1
    Official Full Name
    Cupredoxin superfamily protein
    Primary source
    TAIR:AT1G23010
    Locus tag
    AT1G23010
    See related
    Araport:AT1G23010
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F19G10.5; F19G10_5; Low Phosphate Root1
    Summary
    Encodes a protein with multicopper oxidase activity. Located in ER. Function together with LPR2 (AT1G71040) and a P5-type ATPase (At5g23630/PDR2) in a common pathway that adjusts root meristem activity to Pi (inorganic phosphate) availability.
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    Genomic context

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    See LPR1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (8147118..8149891)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene Heavy metal transport/detoxification superfamily protein Neighboring gene ferric reduction oxidase 3 Neighboring gene miscRNA Neighboring gene ARM repeat superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The function of LPR1 is controlled by an element in the promoter and is independent of SUMO E3 Ligase SIZ1 in response to low Pi stress in Arabidopsis thaliana. Wang X, et al. Plant Cell Physiol, 2010 Mar. PMID 20071375
    2. Long-distance blue light signalling regulates phosphate deficiency-induced primary root growth inhibition. Gao YQ, et al. Mol Plant, 2021 Sep 6. PMID 34102336
    3. Iron-dependent callose deposition adjusts root meristem maintenance to phosphate availability. Müller J, et al. Dev Cell, 2015 Apr 20. PMID 25898169
    4. Root tip contact with low-phosphate media reprograms plant root architecture. Svistoonoff S, et al. Nat Genet, 2007 Jun. PMID 17496893
    5. ER-resident proteins PDR2 and LPR1 mediate the developmental response of root meristems to phosphate availability. Ticconi CA, et al. Proc Natl Acad Sci U S A, 2009 Aug 18. PMID 19666499, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Long-distance blue light signalling regulates phosphate deficiency-induced primary root growth inhibition.
      Title: Long-distance blue light signalling regulates phosphate deficiency-induced primary root growth inhibition.
    2. the LPR1-PDR2 module facilitates, upon Phosphate limitation, cell-specific apoplastic iron and callose deposition in the meristem and elongation zone of primary roots.
      Title: Iron-dependent callose deposition adjusts root meristem maintenance to phosphate availability.
    3. LPR1 is involved in low phosphate stress-regulated primary root growth and signaling pathway, functions independently from PHR1/SIZ1 regulation, and is controlled by the AC-repeat element in the promoter.
      Title: The function of LPR1 is controlled by an element in the promoter and is independent of SUMO E3 Ligase SIZ1 in response to low Pi stress in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    General gene information

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    NM_102149.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to phosphate starvation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cellular response to phosphate starvation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within meristem maintenance IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Cupredoxin superfamily protein
    NP_173714.2
    • Low Phosphate Root1 (LPR1); CONTAINS InterPro DOMAIN/s: Multicopper oxidase, type 3 (InterPro:IPR011707), Multicopper oxidase, type 2 (InterPro:IPR011706), Cupredoxin (InterPro:IPR008972), Multicopper oxidase, type 1 (InterPro:IPR001117); BEST Arabidopsis thaliana protein match is: Cupredoxin superfamily protein (TAIR:AT1G71040.1); Has 3143 Blast hits to 2693 proteins in 814 species: Archae - 12; Bacteria - 2669; Metazoa - 8; Fungi - 64; Plants - 261; Viruses - 0; Other Eukaryotes - 129 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8147118..8149891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102149.4 → NP_173714.2  Cupredoxin superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173714.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I4K5, O23123, Q8GXX3
      UniProtKB/TrEMBL
      A0A654EN20
      Conserved Domains (4) summary
      COG2132
      Location:80 → 579
      SufI; Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA) [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism, Cell wall/membrane/envelope biogenes
      cd13844
      Location:65 → 221
      CuRO_1_BOD_CotA_like; The first Cupredoxin domain of Bilirubin oxidase (BOD), the bacterial endospore coat component CotA, and similar proteins
      cd13868
      Location:234 → 384
      CuRO_2_CotA_like; The second Cupredoxin domain of bacterial laccases including CotA, a bacterial endospore coat component
      cd13891
      Location:413 → 579
      CuRO_3_CotA_like; The third Cupredoxin domain of bacterial laccases including CotA, a bacterial endospore coat component
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4I4K5.1

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