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    GAE2 UDP-D-glucuronate 4-epimerase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839289, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GAE2
    Official Full Name
    UDP-D-glucuronate 4-epimerase 2
    Primary source
    TAIR:AT1G02000
    Locus tag
    AT1G02000
    See related
    Araport:AT1G02000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F22M8.13; F22M8_13; UDP-D-glucuronate 4-epimerase 2
    Summary
    UDP-D-glucuronate 4-epimerase
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    Genomic context

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    See GAE2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (345516..347603)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene FAD-binding Berberine family protein Neighboring gene uncharacterized protein Neighboring gene secretory 1A Neighboring gene nitroreductase family protein Neighboring gene C2H2-like zinc finger protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The biosynthesis of D-Galacturonate in plants. functional cloning and characterization of a membrane-anchored UDP-D-Glucuronate 4-epimerase from Arabidopsis. Mølhøj M, et al. Plant Physiol, 2004 Jul. PMID 15247385, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_100080.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-glucuronate 4-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables UDP-glucuronate 4-epimerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    UDP-D-glucuronate 4-epimerase 2
    NP_171702.1
    • UDP-D-glucuronate 4-epimerase 2 (GAE2); FUNCTIONS IN: UDP-glucuronate 4-epimerase activity, catalytic activity; INVOLVED IN: cellular metabolic process, carbohydrate metabolic process, nucleotide-sugar metabolic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: NAD-dependent epimerase/dehydratase (InterPro:IPR001509), NAD(P)-binding domain (InterPro:IPR016040), Nucleotide sugar epimerase (InterPro:IPR008089); BEST Arabidopsis thaliana protein match is: UDP-D-glucuronate 4-epimerase 3 (TAIR:AT4G00110.1); Has 43438 Blast hits to 43429 proteins in 2985 species: Archae - 785; Bacteria - 25993; Metazoa - 728; Fungi - 385; Plants - 1220; Viruses - 41; Other Eukaryotes - 14286 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      345516..347603
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100080.4 → NP_171702.1  UDP-D-glucuronate 4-epimerase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171702.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WRB6, Q8LFM5, Q9LPC1
      UniProtKB/TrEMBL
      A0A178WEE4, A0A5S9S5I9
      Conserved Domains (1) summary
      cl21454
      Location:94 → 422
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LPC1.1

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