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    TLP6 tubby like protein 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841130, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TLP6
    Official Full Name
    tubby like protein 6
    Primary source
    TAIR:AT1G47270
    Locus tag
    AT1G47270
    See related
    Araport:AT1G47270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtTLP6; F8G22.1; F8G22_1; tubby like protein 6
    Summary
    Member of TLP family
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    Genomic context

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    See TLP6 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (17326530..17328772)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene gamma carbonic anhydrase 2 Neighboring gene 20S proteasome alpha subunit F2 Neighboring gene uncharacterized protein Neighboring gene Cystathionine beta-synthase (CBS) family protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of Arabidopsis Tubby-like proteins and redundant function of AtTLP3 and AtTLP9 in plant response to ABA and osmotic stress. Bao Y, et al. Plant Mol Biol, 2014 Nov. PMID 25168737
    2. Wide-scale screening of T-DNA lines for transcription factor genes affecting male gametophyte development in Arabidopsis. Reňák D, et al. Sex Plant Reprod, 2012 Mar. PMID 22101548
    3. A comprehensive analysis of interaction and localization of Arabidopsis SKP1-like (ASK) and F-box (FBX) proteins. Kuroda H, et al. PLoS One, 2012. PMID 23166809, Free PMC Article
    4. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Smit ME, et al. Plant Cell, 2020 Feb. PMID 31806676, Free PMC Article
    5. Transcriptional regulation of nitrogen-associated metabolism and growth. Gaudinier A, et al. Nature, 2018 Nov. PMID 30356219

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001333268.1
    NM_103621.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    tubby like protein 6
    NP_001185159.1
    • tubby like protein 6 (TLP6); FUNCTIONS IN: phosphoric diester hydrolase activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), F-box domain, Skp2-like (InterPro:IPR022364), Tubby, C-terminal, conserved site (InterPro:IPR018066), Tubby, C-terminal (InterPro:IPR000007); BEST Arabidopsis thaliana protein match is: tubby like protein 2 (TAIR:AT2G18280.2).
    NP_175160.2
    • tubby like protein 6 (TLP6); CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810), F-box domain, Skp2-like (InterPro:IPR022364), Tubby, C-terminal, conserved site (InterPro:IPR018066), Tubby, C-terminal (InterPro:IPR000007); BEST Arabidopsis thaliana protein match is: tubby like protein 2 (TAIR:AT2G18280.2); Has 947 Blast hits to 938 proteins in 117 species: Archae - 0; Bacteria - 0; Metazoa - 351; Fungi - 19; Plants - 464; Viruses - 0; Other Eukaryotes - 113 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      17326530..17328772
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001198230.2 → NP_001185159.1  tubby like protein 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185159.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2DZ75, F4HT64
      Conserved Domains (2) summary
      pfam01167
      Location:132 → 405
      Tub; Tub family
      pfam12937
      Location:68 → 110
      F-box-like; F-box-like

    2. NM_103621.2 → NP_175160.2  tubby like protein 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175160.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WPY0, Q9C6B4
      UniProtKB/TrEMBL
      A0A7G2DZ75
      Conserved Domains (2) summary
      pfam01167
      Location:133 → 406
      Tub; Tub family
      pfam12937
      Location:69 → 111
      F-box-like; F-box-like

    3. NM_001333268.1 → NP_001322089.1  tubby like protein 6 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8ASW8, A0A7G2DZ75
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WPY0.1

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