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    GPAT4 glycerol-3-phosphate acyltransferase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839297, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GPAT4
    Official Full Name
    glycerol-3-phosphate acyltransferase 4
    Primary source
    TAIR:AT1G01610
    Locus tag
    AT1G01610
    See related
    Araport:AT1G01610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATGPAT4; F22L4.15; F22L4_15; glycerol-3-phosphate acyltransferase 4; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4; GLYCEROL-3-PHOSPHATE sn-2-ACYLTRANSFERASE 4
    Summary
    bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase. Involved in cutin assembly and is functionally redundant with GPAT8.
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    Genomic context

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    See GPAT4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (221642..224351, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ferric reduction oxidase 1 Neighboring gene cytochrome P450, family 86, subfamily A, polypeptide 4 Neighboring gene plasma membrane intrinsic protein 1C Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene BTB/POZ domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Function identification of Arabidopsis GPAT4 and GPAT8 in the biosynthesis of suberin and cuticular wax. Zhang X, et al. Plant Sci, 2024 Feb. PMID 38036221
    2. Identification of acyltransferases required for cutin biosynthesis and production of cutin with suberin-like monomers. Li Y, et al. Proc Natl Acad Sci U S A, 2007 Nov 13. PMID 17991776, Free PMC Article
    3. A land-plant-specific glycerol-3-phosphate acyltransferase family in Arabidopsis: substrate specificity, sn-2 preference, and evolution. Yang W, et al. Plant Physiol, 2012 Oct. PMID 22864585, Free PMC Article
    4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Function identification of Arabidopsis GPAT4 and GPAT8 in the biosynthesis of suberin and cuticular wax.
      Title: Function identification of Arabidopsis GPAT4 and GPAT8 in the biosynthesis of suberin and cuticular wax.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_100043.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycerol-3-phosphate 2-O-acyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cutin biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    glycerol-3-phosphate acyltransferase 4
    NP_171667.1
    • glycerol-3-phosphate acyltransferase 4 (GPAT4); FUNCTIONS IN: 1-acylglycerol-3-phosphate O-acyltransferase activity, acyltransferase activity; INVOLVED IN: metabolic process, cutin biosynthetic process; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Phospholipid/glycerol acyltransferase (InterPro:IPR002123); BEST Arabidopsis thaliana protein match is: glycerol-3-phosphate acyltransferase 8 (TAIR:AT4G00400.1); Has 410 Blast hits to 396 proteins in 34 species: Archae - 0; Bacteria - 20; Metazoa - 10; Fungi - 0; Plants - 373; Viruses - 0; Other Eukaryotes - 7 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      221642..224351 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100043.5 → NP_171667.1  glycerol-3-phosphate acyltransferase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171667.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W4N0, Q9LMM0
      UniProtKB/TrEMBL
      A0A178W9F8, A0A5S9S493, A0A7G2EU02
      Conserved Domains (1) summary
      PLN02177
      Location:6 → 500
      PLN02177; glycerol-3-phosphate acyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LMM0.1

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