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    SEP2 K-box region and MADS-box transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821151, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SEP2
    Official Full Name
    K-box region and MADS-box transcription factor family protein
    Primary source
    TAIR:AT3G02310
    Locus tag
    AT3G02310
    See related
    Araport:AT3G02310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AGAMOUS-like 4; AGL4; F14P3.4; F14P3_4; SEPALLATA 2; TRANSCRIPTION FACTOR
    Summary
    MADS-box protein, binds K domain of AG in vivo
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    Genomic context

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    See SEP2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (464279..467151, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene Regulator of chromosome condensation (RCC1) family protein Neighboring gene tRNA-Ile Neighboring gene N2,N2-dimethylguanosine tRNA methyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FAR-RED ELONGATED HYPOCOTYL3 activates SEPALLATA2 but inhibits CLAVATA3 to regulate meristem determinacy and maintenance in Arabidopsis. Li D, et al. Proc Natl Acad Sci U S A, 2016 Aug 16. PMID 27469166, Free PMC Article
    2. Arabidopsis SEPALLATA proteins differ in cooperative DNA-binding during the formation of floral quartet-like complexes. Jetha K, et al. Nucleic Acids Res, 2014. PMID 25183521, Free PMC Article
    3. AGL1-AGL6, an Arabidopsis gene family with similarity to floral homeotic and transcription factor genes. Ma H, et al. Genes Dev, 1991 Mar. PMID 1672119
    4. Specific interactions between the K domains of AG and AGLs, members of the MADS domain family of DNA binding proteins. Fan HY, et al. Plant J, 1997 Nov. PMID 9418042
    5. MADS-box protein complexes control carpel and ovule development in Arabidopsis. Favaro R, et al. Plant Cell, 2003 Nov. PMID 14555696, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CLV3, SEPALLATA1 (SEP1), and SEP2 are FHY3 target genes.
      Title: FAR-RED ELONGATED HYPOCOTYL3 activates SEPALLATA2 but inhibits CLAVATA3 to regulate meristem determinacy and maintenance in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001337399.1
    NM_111098.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within flower development NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within plant ovule development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    K-box region and MADS-box transcription factor family protein
    NP_186880.1
    • SEPALLATA 2 (SEP2); FUNCTIONS IN: protein binding, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: flower development, ovule development; LOCATED IN: nucleus; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100), Transcription factor, K-box (InterPro:IPR002487); BEST Arabidopsis thaliana protein match is: K-box region and MADS-box transcription factor family protein (TAIR:AT5G15800.1); Has 7363 Blast hits to 7362 proteins in 916 species: Archae - 3; Bacteria - 0; Metazoa - 630; Fungi - 305; Plants - 6350; Viruses - 0; Other Eukaryotes - 75 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      464279..467151 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111098.4 → NP_186880.1  K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186880.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P29384
      UniProtKB/TrEMBL
      A0A178V680, A0A384L9U7, A0A5S9X8E8, Q5XXL4, Q5XXL5, Q84WB0
      Conserved Domains (2) summary
      cd00265
      Location:2 → 77
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
      pfam01486
      Location:84 → 173
      K-box; K-box region

    2. NM_001337399.1 → NP_001325746.1  K-box region and MADS-box transcription factor family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LM64
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P29384.1

    Gene LinkOut

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