U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    NANA Eukaryotic aspartyl protease family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820452, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NANA
    Official Full Name
    Eukaryotic aspartyl protease family protein
    Primary source
    TAIR:AT3G12700
    Locus tag
    AT3G12700
    See related
    Araport:AT3G12700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Summary
    Encodes an aspartic protease has an important regulatory function in chloroplasts that not only influences photosynthetic carbon metabolism but also plastid and nuclear gene expression.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See NANA in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (4036945..4039185)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Acid phosphatase/vanadium-dependent haloperoxidase-related protein Neighboring gene AGC kinase 1.5 Neighboring gene DNA glycosylase superfamily protein Neighboring gene myb domain protein 67

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Misexpression of a chloroplast aspartyl protease leads to severe growth defects and alters carbohydrate metabolism in Arabidopsis. Paparelli E, et al. Plant Physiol, 2012 Nov. PMID 22987884, Free PMC Article
    2. [The gene NANA regulates cell proliferation in Arabidopsis thaliana shoot apical meristem without interaction with CLV1, CLV2, CLV3]. Al'bert AV, et al. Ontogenez, 2014 Sep-Oct. PMID 25752149
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Gene NANA regulates cell proliferation in Arabidopsis thaliana shoot apical meristem. [NANA]
      Title: [The gene NANA regulates cell proliferation in Arabidopsis thaliana shoot apical meristem without interaction with CLV1, CLV2, CLV3].
    2. NANA aspartic protease has an important regulatory function in chloroplasts.[NANA]
      Title: Misexpression of a chloroplast aspartyl protease leads to severe growth defects and alters carbohydrate metabolism in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help
    NM_001161138.1
    NM_001338006.1
    NM_112106.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aspartic-type endopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within carbohydrate metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast-nucleus signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in circadian rhythm IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to sucrose IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Eukaryotic aspartyl protease family protein
    NP_001154610.1
    • Eukaryotic aspartyl protease family protein; FUNCTIONS IN: aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: cellular_component unknown; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase aspartic (InterPro:IPR021109), Peptidase aspartic, catalytic (InterPro:IPR009007), Peptidase A1 (InterPro:IPR001461), Peptidase aspartic, active site (InterPro:IPR001969); BEST Arabidopsis thaliana protein match is: Eukaryotic aspartyl protease family protein (TAIR:AT1G31450.1); Has 1235 Blast hits to 1233 proteins in 174 species: Archae - 0; Bacteria - 0; Metazoa - 160; Fungi - 149; Plants - 889; Viruses - 0; Other Eukaryotes - 37 (source: NCBI BLink).
    NP_187876.2
    • Eukaryotic aspartyl protease family protein; FUNCTIONS IN: aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: cellular_component unknown; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase aspartic (InterPro:IPR021109), Peptidase aspartic, catalytic (InterPro:IPR009007), Peptidase A1 (InterPro:IPR001461), Peptidase aspartic, active site (InterPro:IPR001969); BEST Arabidopsis thaliana protein match is: Eukaryotic aspartyl protease family protein (TAIR:AT3G25700.1); Has 3537 Blast hits to 3526 proteins in 338 species: Archae - 0; Bacteria - 0; Metazoa - 933; Fungi - 442; Plants - 1963; Viruses - 0; Other Eukaryotes - 199 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      4036945..4039185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112106.4 → NP_187876.2  Eukaryotic aspartyl protease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187876.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4J9V9, Q8VYM5, Q9LTW4
      UniProtKB/TrEMBL
      A0A5S9XBG8, A0A654F6H6
      Conserved Domains (1) summary
      cd05476
      Location:105 → 460
      pepsin_A_like_plant; Chroloplast Nucleoids DNA-binding Protease and Nucellin, pepsin-like aspartic proteases from plants

    2. NM_001161138.1 → NP_001154610.1  Eukaryotic aspartyl protease family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154610.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LTW4
      Conserved Domains (1) summary
      cl11403
      Location:106 → 160
      pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases

    3. NM_001338006.1 → NP_001326382.1  Eukaryotic aspartyl protease family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LP40
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LTW4.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.