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    CEF uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823559, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CEF
    Official Full Name
    uncharacterized protein
    Primary source
    TAIR:AT3G44340
    Locus tag
    AT3G44340
    See related
    Araport:AT3G44340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    clone eighty-four
    Summary
    homologous to yeast and animal Sec24 proteins; expression in yeast cells enhances their survival under oxidative stress conditions.
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    Genomic context

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    See CEF in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    26
    Sequence:
    Chromosome: 3; NC_003074.8 (16011547..16020336, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene M28 Zn-peptidase nicastrin Neighboring gene ncRNA Neighboring gene NAC domain containing protein 61

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CEF, a sec24 homologue of Arabidopsis thaliana, enhances the survival of yeast under oxidative stress conditions. Belles-Boix E, et al. J Exp Bot, 2000 Oct. PMID 11053466
    2. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    3. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
    4. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
    5. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001035731.2
    NM_001339129.1
    NM_001339130.1
    NM_001339131.1
    NM_114302.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to oxidative stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of COPII vesicle coat IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_001030808.1
    • clone eighty-four (CEF); FUNCTIONS IN: transporter activity, zinc ion binding; INVOLVED IN: response to oxidative stress, vesicle-mediated transport; LOCATED IN: COPII vesicle coat, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sec23/Sec24, helical domain (InterPro:IPR006900), Sec23/Sec24 beta-sandwich (InterPro:IPR012990), Sec23/Sec24, trunk domain (InterPro:IPR006896), Zinc finger, Sec23/Sec24-type (InterPro:IPR006895), Gelsolin domain (InterPro:IPR007123); BEST Arabidopsis thaliana protein match is: Sec23/Sec24 protein transport family protein (TAIR:AT4G32640.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_566869.1
    • clone eighty-four (CEF); FUNCTIONS IN: transporter activity, zinc ion binding; INVOLVED IN: response to oxidative stress, vesicle-mediated transport; LOCATED IN: COPII vesicle coat, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Sec23/Sec24, helical domain (InterPro:IPR006900), Sec23/Sec24 beta-sandwich (InterPro:IPR012990), Sec23/Sec24, trunk domain (InterPro:IPR006896), Zinc finger, Sec23/Sec24-type (InterPro:IPR006895), Gelsolin domain (InterPro:IPR007123); BEST Arabidopsis thaliana protein match is: Sec23/Sec24 protein transport family protein (TAIR:AT4G32640.2); Has 125534 Blast hits to 60845 proteins in 1833 species: Archae - 62; Bacteria - 18823; Metazoa - 61754; Fungi - 17926; Plants - 11260; Viruses - 2145; Other Eukaryotes - 13564 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      16011547..16020336 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114302.3 → NP_566869.1  uncharacterized protein AT3G44340 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566869.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LQT4, F4J1Y1, Q9M291
      UniProtKB/TrEMBL
      A0A178VC24
      Conserved Domains (6) summary
      COG5028
      Location:221 → 1092
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      cd01479
      Location:505 → 749
      Sec24-like; Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes ...
      pfam00626
      Location:964 → 1021
      Gelsolin; Gelsolin repeat
      pfam04810
      Location:430 → 467
      zf-Sec23_Sec24; Sec23/Sec24 zinc finger
      pfam04815
      Location:851 → 941
      Sec23_helical; Sec23/Sec24 helical domain
      pfam08033
      Location:750 → 834
      Sec23_BS; Sec23/Sec24 beta-sandwich domain

    2. NM_001339130.1 → NP_001326945.1  uncharacterized protein AT3G44340 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LQT4, F4J1Y1, Q9M291
      UniProtKB/TrEMBL
      A0A178VC24

    3. NM_001339129.1 → NP_001326943.1  uncharacterized protein AT3G44340 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A1I9LQT4, F4J1Y1, Q9M291
      UniProtKB/TrEMBL
      A0A178VC24

    4. NM_001035731.2 → NP_001030808.1  uncharacterized protein AT3G44340 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030808.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VC24, F4J1Y2
      Conserved Domains (6) summary
      COG5028
      Location:221 → 1066
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      cd01479
      Location:505 → 749
      Sec24-like; Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes ...
      pfam00626
      Location:964 → 1021
      Gelsolin; Gelsolin repeat
      pfam04810
      Location:430 → 467
      zf-Sec23_Sec24; Sec23/Sec24 zinc finger
      pfam04815
      Location:851 → 941
      Sec23_helical; Sec23/Sec24 helical domain
      pfam08033
      Location:750 → 834
      Sec23_BS; Sec23/Sec24 beta-sandwich domain

    5. NM_001339131.1 → NP_001326944.1  uncharacterized protein AT3G44340 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VC24, F4J1Y2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M291.3

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