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    Radical SAM superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836449, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Radical SAM superfamily protein
    Primary source
    TAIR:AT5G63290
    Locus tag
    AT5G63290
    See related
    Araport:AT5G63290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MDC12.26; MDC12_26
    Summary
    CPO3 (At5g63290) has not been characterized per se, but is a homolog of the CPDH/HEMN (see review by Layer et al, 2010). The homolog from cyanobacteria was recently characterized to be a CPDH (see Goto et al, 2010), but not yet from plants.
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (25369245..25370940, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene RPM1-interacting protein 4 (RIN4) family protein Neighboring gene C2H2-like zinc finger protein Neighboring gene ncRNA Neighboring gene Ribosomal protein S21 family protein Neighboring gene nucleoside diphosphate kinase 2 Neighboring gene ncRNA Neighboring gene nuclear protein X1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gametophyte Development Needs Mitochondrial Coproporphyrinogen III Oxidase Function. Pratibha P, et al. Plant Physiol, 2017 May. PMID 28270625, Free PMC Article
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_125724.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables coproporphyrinogen oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in porphyrin-containing compound biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Radical SAM superfamily protein
    NP_201134.1
    • Radical SAM superfamily protein; FUNCTIONS IN: oxidoreductase activity, iron-sulfur cluster binding, coproporphyrinogen oxidase activity, catalytic activity; INVOLVED IN: oxidation reduction, porphyrin biosynthetic process; LOCATED IN: chloroplast, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Putative oxygen-independent coproporphyrinogen III oxidase (InterPro:IPR004559), HemN, C-terminal (InterPro:IPR010723), Radical SAM (InterPro:IPR007197); Has 10146 Blast hits to 10146 proteins in 2456 species: Archae - 113; Bacteria - 8401; Metazoa - 78; Fungi - 4; Plants - 37; Viruses - 0; Other Eukaryotes - 1513 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25369245..25370940 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125724.3 → NP_201134.1  Radical SAM superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201134.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UBY4, A0A654GDL6, Q9FMJ4
      Conserved Domains (1) summary
      PRK07379
      Location:54 → 479
      PRK07379; coproporphyrinogen III oxidase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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