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    SNL2 SIN3-like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831354, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SNL2
    Official Full Name
    SIN3-like 2
    Primary source
    TAIR:AT5G15020
    Locus tag
    AT5G15020
    See related
    Araport:AT5G15020
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F2G14.140; F2G14_140; SIN3-like 2
    Summary
    Encodes a homolog of the transcriptional repressor SIN3 (AT1G24190).
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    Genomic context

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    See SNL2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    23
    Sequence:
    Chromosome: 5; NC_003076.8 (4859127..4866034, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis paired amphipathic helix proteins SNL1 and SNL2 redundantly regulate primary seed dormancy via abscisic acid-ethylene antagonism mediated by histone deacetylation. Wang Z, et al. Plant Cell, 2013 Jan. PMID 23371947, Free PMC Article
    2. Photoperiodic regulation of flowering time through periodic histone deacetylation of the florigen gene FT. Gu X, et al. PLoS Biol, 2013 Sep. PMID 24019760, Free PMC Article
    3. Arabidopsis RPD3-like histone deacetylases form multiple complexes involved in stress response. Feng C, et al. J Genet Genomics, 2021 May 20. PMID 34144927
    4. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SNL1 and SNL2 regulate seed dormancy by mediating the abscisic acid (ABA)-ethylene antagonism in Arabidopsis. SNL1 and SNL2 could represent a cross-link point of the ABA and ethylene pathways in the regulation of seed dormancy.
      Title: Arabidopsis paired amphipathic helix proteins SNL1 and SNL2 redundantly regulate primary seed dormancy via abscisic acid-ethylene antagonism mediated by histone deacetylation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203382.2
    NM_121506.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Sin3-type complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SIN3-like 2
    NP_001190311.1
    • SIN3-like 2 (SNL2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone deacetylase interacting (InterPro:IPR013194), Paired amphipathic helix (InterPro:IPR003822); BEST Arabidopsis thaliana protein match is: SIN3-like 1 (TAIR:AT3G01320.1).
    NP_197006.2
    • SIN3-like 2 (SNL2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone deacetylase interacting (InterPro:IPR013194), Paired amphipathic helix (InterPro:IPR003822); BEST Arabidopsis thaliana protein match is: SIN3-like 1 (TAIR:AT3G01320.1); Has 7665 Blast hits to 4944 proteins in 497 species: Archae - 53; Bacteria - 740; Metazoa - 2798; Fungi - 1391; Plants - 712; Viruses - 253; Other Eukaryotes - 1718 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4859127..4866034 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203382.2 → NP_001190311.1  SIN3-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190311.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UE26, F4K8B0
      Conserved Domains (4) summary
      smart00761
      Location:462 → 558
      HDAC_interact; Histone deacetylase (HDAC) interacting
      PHA03169
      Location:788 → 1031
      PHA03169; hypothetical protein; Provisional
      pfam02671
      Location:154 → 197
      PAH; Paired amphipathic helix repeat
      pfam16879
      Location:1074 → 1322
      Sin3a_C; C-terminal domain of Sin3a protein

    2. NM_121506.4 → NP_197006.2  SIN3-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197006.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GWB6, Q9LFQ3
      UniProtKB/TrEMBL
      A0A178UE26
      Conserved Domains (4) summary
      smart00761
      Location:462 → 558
      HDAC_interact; Histone deacetylase (HDAC) interacting
      PHA03169
      Location:788 → 1031
      PHA03169; hypothetical protein; Provisional
      pfam02671
      Location:154 → 197
      PAH; Paired amphipathic helix repeat
      pfam16879
      Location:1074 → 1334
      Sin3a_C; C-terminal domain of Sin3a protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LFQ3.2

    Gene LinkOut

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