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    bard bard [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42161, updated on 27-Dec-2024

    Summary

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    Official Symbol
    bardprovided by FlyBase
    Official Full Name
    bardprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038566
    Locus tag
    Dmel_CG14317
    See related
    AllianceGenome:FB:FBgn0038566
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0172774.95; CG14317; Dmel\CG14317
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including antennal anlage; antennal primordium; anterior endoderm anlage; central brain anlage; and head epidermis primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See bard in Genome Data Viewer
    Location:
    90E4-90E4; 3-62 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18081048..18082583)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13906770..13908305)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene heartless Neighboring gene transfer RNA:Glycine-TCC 1-3 Neighboring gene transfer RNA:Glycine-TCC 1-4 Neighboring gene stripe

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The F-box protein Bard (CG14317) targets the Smaug RNA-binding protein for destruction during the Drosophila maternal-to-zygotic transition. Cao WX, et al. Genetics, 2022 Jan 4. PMID 34757425, Free PMC Article
    2. Drosophila acid DNase is a homolog of mammalian DNase II. Evans CJ, et al. Gene, 2002 Jul 24. PMID 12242012
    3. Structural basis for binding of Drosophila Smaug to the GPCR Smoothened and to the germline inducer Oskar. Kubíková J, et al. Proc Natl Acad Sci U S A, 2023 Aug 8. PMID 37523566, Free PMC Article
    4. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cao WX, et al. Cell Rep, 2020 Jun 23. PMID 32579915, Free PMC Article
    5. A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila. Dui W, et al. J Genet Genomics, 2012 Aug 20. PMID 22884096

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The F-box protein Bard (CG14317) targets the Smaug RNA-binding protein for destruction during the Drosophila maternal-to-zygotic transition.
      Title: The F-box protein Bard (CG14317) targets the Smaug RNA-binding protein for destruction during the Drosophila maternal-to-zygotic transition.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
    Inferred from Sequence Model
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    bard
    Names
    CG14317-PA
    bard-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18081048..18082583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142418.2 → NP_650675.1  bard [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650675.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VED4
      Related
      FBpp0082965
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VED4 Q9VED4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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