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    Zfp981 zinc finger protein 981 [ Mus musculus (house mouse) ]

    Gene ID: 100041433, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp981provided by MGI
    Official Full Name
    zinc finger protein 981provided by MGI
    Primary source
    MGI:MGI:3700965
    See related
    Ensembl:ENSMUSG00000056300 AllianceGenome:MGI:3700965
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm13247
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF616 (zinc finger protein 616). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Zfp981 in Genome Data Viewer
    Location:
    4 E1; 4 78.3 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (146586457..146623852)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (146502000..146539395)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr4:145746825-145747126 Neighboring gene STARR-positive B cell enhancer ABC_E6263 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145737763-145738064 Neighboring gene zinc finger protein 992 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145736397-145736698 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145733036-145733337 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145715582-145715883 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145714381-145714682 Neighboring gene carnitine deficiency-associated gene expressed in ventricle 3 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr4:145711415-145711716 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145707828-145708129 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145704476-145704777 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145703390-145703691 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145702225-145702525 Neighboring gene STARR-seq mESC enhancer starr_12041 Neighboring gene RIKEN cDNA 1700095A21 gene Neighboring gene STARR-positive B cell enhancer mm9_chr4:145660367-145660668 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145657520-145657821 Neighboring gene predicted gene 13237 Neighboring gene protein phosphatase 2, regulatory subunit B', alpha pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC100041433

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243138.1 → NP_001230067.1  uncharacterized protein LOC100041433

      See identical proteins and their annotated locations for NP_001230067.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL627077
      Consensus CDS
      CCDS57311.1
      UniProtKB/TrEMBL
      A2A8V7
      Related
      ENSMUSP00000101361.3, ENSMUST00000105735.9
      Conserved Domains (5) summary
      smart00349
      Location:13 → 55
      KRAB; krueppel associated box
      COG5048
      Location:45 → 410
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:269 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:309 → 334
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001243139.1 → NP_001230068.1  uncharacterized protein LOC100041433

      See identical proteins and their annotated locations for NP_001230068.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has a different 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL627077
      Consensus CDS
      CCDS57311.1
      UniProtKB/TrEMBL
      A2A8V7
      Related
      ENSMUSP00000136739.2, ENSMUST00000179175.3
      Conserved Domains (5) summary
      smart00349
      Location:13 → 55
      KRAB; krueppel associated box
      COG5048
      Location:45 → 410
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:269 → 289
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:13 → 52
      KRAB; KRAB box
      pfam13465
      Location:309 → 334
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      146586457..146623852
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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