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    CG3491 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34870, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3491provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028887
    Locus tag
    Dmel_CG3491
    See related
    AllianceGenome:FB:FBgn0028887
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS03323.1; Dmel\CG3491
    Summary
    Predicted to enable chromatin DNA binding activity and histone binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to several human genes including SBNO1 (strawberry notch homolog 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3491 in Genome Data Viewer
    Location:
    35B7-35B7; 2-50 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (14924590..14930565)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (14924590..14930565)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45302 Neighboring gene Protamine B Neighboring gene sidestep II Neighboring gene long non-coding RNA:CR45331 Neighboring gene moladietz

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic variation in natural populations of Drosophila melanogaster. Langley CH, et al. Genetics, 2012 Oct. PMID 22673804, Free PMC Article
    2. WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes. David-Morrison G, et al. Dev Cell, 2016 Jan 25. PMID 26812014, Free PMC Article
    3. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Ashburner M, et al. Genetics, 1999 Sep. PMID 10471707, Free PMC Article
    4. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    5. A Comprehensive Drosophila melanogaster Transcription Factor Interactome. Shokri L, et al. Cell Rep, 2019 Apr 16. PMID 30995488, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables chromatin DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3491-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      14924590..14930565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135887.3 → NP_609731.1  uncharacterized protein Dmel_CG3491 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609731.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V453
      Related
      FBpp0080237
      Conserved Domains (3) summary
      smart00487
      Location:759 → 986
      DEXDc; DEAD-like helicases superfamily
      pfam13871
      Location:1297 → 1576
      Helicase_C_4; C-terminal domain on Strawberry notch homologue
      pfam13872
      Location:737 → 1038
      AAA_34; P-loop containing NTP hydrolase pore-1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MSP6 Q8MSP6
    Q9V453 Q9V453

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