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    Polr3H RNA polymerase III subunit H [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39310, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Polr3Hprovided by FlyBase
    Official Full Name
    RNA polymerase III subunit Hprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036188
    Locus tag
    Dmel_CG7339
    See related
    AllianceGenome:FB:FBgn0036188
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7339; Dmel\CG7339; lincRNA.S4825; RPC25
    Summary
    Predicted to be involved in transcription initiation at RNA polymerase III promoter. Predicted to be part of RNA polymerase III complex. Orthologous to human POLR3H (RNA polymerase III subunit H). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Polr3H in Genome Data Viewer
    Location:
    68D1-68D1; 3-36 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11648756..11650499)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11641856..11643599)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene RIO kinase 1 Neighboring gene uncharacterized protein Neighboring gene mir-274 stem loop Neighboring gene long non-coding RNA:CR45881

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Tendon Cell Specific RNAi Screen Reveals Novel Candidates Essential for Muscle Tendon Interaction. Tiwari P, et al. PLoS One, 2015. PMID 26488612, Free PMC Article
    2. In silico identification of Drosophila melanogaster genes encoding RNA polymerase subunits. Marygold SJ, et al. MicroPubl Biol, 2020 Oct 20. PMID 33274328, Free PMC Article
    3. A transcriptome-wide RNAi screen in the Drosophila ovary reveals factors of the germline piRNA pathway. Czech B, et al. Mol Cell, 2013 Jun 6. PMID 23665227, Free PMC Article
    4. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
    5. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transcription initiation at RNA polymerase III promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RNA polymerase III subunit H
    Names
    CG7339-PA
    CG7339-PB
    Polr3H-PA
    Polr3H-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11648756..11650499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274791.1 → NP_001261720.1  RNA polymerase III subunit H, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261720.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTL6
      Conserved Domains (3) summary
      COG1095
      Location:1 → 212
      RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]
      cd04330
      Location:2 → 81
      RNAP_III_Rpc25_N; RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, ...
      pfam08292
      Location:79 → 212
      RNA_pol_Rbc25; RNA polymerase III subunit Rpc25

    2. NM_140233.2 → NP_648490.1  RNA polymerase III subunit H, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648490.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTL6
      Related
      FBpp0075838
      Conserved Domains (3) summary
      COG1095
      Location:1 → 212
      RPB7; DNA-directed RNA polymerase, subunit E'/Rpb7 [Transcription]
      cd04330
      Location:2 → 81
      RNAP_III_Rpc25_N; RNAP_III_Rpc25_N: Rpc25, N-terminal ribonucleoprotein (RNP) domain. Rpc25 is a subunit of eukaryotic RNA polymerase (RNAP) III and is homologous to Rpa43 of eukaryotic RNAP I, Rpb7 of eukaryotic RNAP II, and RpoE of archaeal RNAP. Rpc25 has two domains, ...
      pfam08292
      Location:79 → 212
      RNA_pol_Rbc25; RNA polymerase III subunit Rpc25
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTL6 Q9VTL6

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