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    CG7579 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39714, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7579provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036528
    Locus tag
    Dmel_CG7579
    See related
    AllianceGenome:FB:FBgn0036528
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7579; dppGalNAcT12
    Summary
    Predicted to be involved in oligosaccharide biosynthetic process and protein O-linked glycosylation. Predicted to be active in Golgi apparatus. Is expressed in adult head. Orthologous to human GALNTL6 (polypeptide N-acetylgalactosaminyltransferase like 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7579 in Genome Data Viewer
    Location:
    71F1-71F1; 3-43 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15681633..15683445, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15674733..15676545, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Polypeptide N-Acetylgalactosaminyltransferase 8 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster. Ten Hagen KG, et al. J Biol Chem, 2003 Sep 12. PMID 12829714
    2. Expression of the UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase family is spatially and temporally regulated during Drosophila development. Tian E, et al. Glycobiology, 2006 Feb. PMID 16251381
    3. A Forward Genetic Approach to Mapping a P-Element Second Site Mutation Identifies DCP2 as a Novel Tumor Suppressor in Drosophila melanogaster. Mishra R, et al. G3 (Bethesda), 2020 Aug 5. PMID 32591349, Free PMC Article
    4. Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila. Schwientek T, et al. J Biol Chem, 2002 Jun 21. PMID 11925450
    5. Functional and phylogenetic analyses of a putative Drosophila melanogaster UDP-glycosyltransferase gene. Luque T, et al. Insect Biochem Mol Biol, 2002 Dec. PMID 12429111

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables polypeptide N-acetylgalactosaminyltransferase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in oligosaccharide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein O-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7579-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15681633..15683445 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140542.2 → NP_648799.1  uncharacterized protein Dmel_CG7579 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648799.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IA41, Q9VUT5
      Related
      FBpp0075334
      Conserved Domains (4) summary
      cd02510
      Location:54 → 349
      pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
      COG0463
      Location:52 → 336
      WcaA; Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]
      cd00161
      Location:367 → 478
      RICIN; Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific ...
      pfam00652
      Location:373 → 476
      Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IA41.1 Q8IA41

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